(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
|
|
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Eigenschaften
- Schmelzpunkt:
- 165-167 °C
- Siedepunkt:
- 545.9±35.0 °C(Predicted)
- Dichte
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- L?slichkeit
- DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
- Aggregatzustand
- A solid
- pka
- 4.74±0.10(Predicted)
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alarmwort | Warnung | ||||||||||||||
Gefahrenhinweise |
|
||||||||||||||
Sicherheit |
|
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
12-keto Lithocholic acid is a metabolite of the secondary bile acid deoxycholic acid (DCA; Item Nos. 20756 | 18231). Fecal levels of 12-keto lithocholic acid are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol , hyodeoxycholic acid (HDCA; ), or lithocholic acid (LCA; ). 12-keto Lithocholic acid activates the human pregnane X receptor (PXR; EC50 = 31.3 μM in a cell-based transactivation assay). 12-keto Lithocholic acid levels are increased in duodenal bile from patients with type 2 diabetes.(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 36)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
Guangzhou CATO Research Chemicals Inc. | +86-020-81960175-617 +8615602392859 |
Intermediate@cato-chem.com | China | 8322 | 58 |
Moxin Chemicals | +8617320513646 |
mike@molcoo.com | China | 9511 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 18070 | 56 |
Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 |
2853979815@qq.com | China | 10006 | 55 |
Beijing YiboYuntian Technology Co., Ltd. | 13811826434 |
lichen13811826434@126.com | China | 565 | 58 |
Aikon International Limited | 025-66113011 18112977050 |
sales01@aikonchem.com | China | 16027 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; |
sales@rrkchem.com | China | 57423 | 58 |
5130-29-0()Verwandte Suche:
- (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
- 12-Ketodeoxycholic acid
- 3-ALPHA-HYDROXY-12-OXO-5-BETA-CHOLANOICACID
- Cholic Acid IMpurity (3-alpha-Hydroxy-12-Oxo-5-beta-Cholanoic Acid)
- (4R)-4-((3R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- Cholic Acid Impurity 9
- 5β-CHOLANIC acid-3α-OL-12-ONE
- (R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- acid,chronic,12Ketodeoxycholic acid,kidney,12 Ketodeoxycholic acid,Inhibitor,injury,NAFLD,Aristolochic,nephropathy,inhibit,Endogenous Metabolite,AAN,disease,12-Ketodeoxycholic acid
- Cholan-24-oic acid, 3-hydroxy-12-oxo-, (3α,5β)-
- 5β-CHOLANIC ACID-3α-OL-12-ONE
- 5130-29-0