Entacapone Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Comtan,Orion Corporation

Manufacturing Process

N,N-Diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide (2- Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl).
A solution containing 1.83 g of 3,4-dihydroxy-5-nitrobenzaldehyde, 1.5 g of N,N-diethylcyanoacetamide and catalytic amount of piperidine acetate in 40 ml of dry ethanol was refluxed over night. After cooling the solvent was evaporated in vacuo and the residue was recrystallized from waterdimethylformamide. Yield of desired product was 2.23 g (73%), melting point 153°-156°C.

Therapeutic Function

Antiparkinsonian

Entacapone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Entacapone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hangzhou Yuhao Chemical Technology Co., Ltd	0571-82693216	info@yuhaochemical.com	China	9387	52
Hubei XinyuanShun Chemical Co., Ltd.	13971561712, 13995564702, 027-50664929	hbeixys2001@163.com	China	3120	55
Shanghai QianYan Bio-technology Co., Ltd	02781293128	orders@biochemsafebuy.com	China	9923	55
Foshan DaoQi Biological Co., Ltd.	18062666947	2355880548@qq.com	China	4228	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4988	58

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• N,N-Diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide
• (E)-2-Cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide
• 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide
• C071192
• Novartis brand of entacapone
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-
• 116314-67-1