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ARV-471

ARV-471 Struktur
2229711-68-4
CAS-Nr.
2229711-68-4
Englisch Name:
ARV-471
Synonyma:
ARV-471;Vepdegestrant;Vepdegestrant(ARV-471);ARV-471, 10 mM in DMSO;3-(4-hydroxy-6-methyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione;(S)-3-(5-(4-((1-(4-((1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione;oral,Inhibitor,breast cancer,PROTAC,E3 ligase,inhibit,hetero-bifunctional,ubiquitylation,ARV-471,PROTACs,Estrogen Receptor/ERR,ARV 471,estrogen receptor,ARV471,proteasome;2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-
CBNumber:
CB48816045
Summenformel:
C45H49N5O4
Molgewicht:
723.9
MOL-Datei:
2229711-68-4.mol

ARV-471 Eigenschaften

Dichte
1.275±0.06 g/cm3(Predicted)
L?slichkeit
DMSO : 110 mg/mL (151.95 mM; Need ultrasonic)
Aggregatzustand
Solid
pka
10.36±0.60(Predicted)
Farbe
White to off-white

Sicherheit

ARV-471 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. It is developed for the research of breast cancer.

ARV-471 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ARV-471 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 55)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32965 60
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 8497 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Xilinglab Co., Ltd.
+8618381337976
bd@xilinglab.com China 86 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Moxin Chemicals
+8617320513646
mike@molcoo.com China 9558 58
Tianjin Lanshu Pharmaceutical Technology Co., Ltd 15210678165
hanyachao@163.com China 13 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581
sales@chemhifuture.com China 3021 58

  • 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-
  • ARV-471
  • Vepdegestrant
  • Vepdegestrant(ARV-471)
  • (S)-3-(5-(4-((1-(4-((1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
  • oral,Inhibitor,breast cancer,PROTAC,E3 ligase,inhibit,hetero-bifunctional,ubiquitylation,ARV-471,PROTACs,Estrogen Receptor/ERR,ARV 471,estrogen receptor,ARV471,proteasome
  • 3-(4-hydroxy-6-methyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione
  • ARV-471, 10 mM in DMSO
  • 2229711-68-4
  • C45H49N5O4
  • t2z001
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