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5-(TETRADECYLOXY)-2-FUROIC ACID

5-(TETRADECYLOXY)-2-FUROIC ACID Struktur
54857-86-2
CAS-Nr.
54857-86-2
Englisch Name:
5-(TETRADECYLOXY)-2-FUROIC ACID
Synonyma:
TOFA;mdl14514;RMI-14514;TOFA (RMI14514;RMI14514; MDL14514;TOFA (RMI14514:MDL14514);5-tetradecyloxy-2-furonicacid;5-(TETRADECYLOXY)-2-FUROIC ACID;5-(TETRADECYLOXY)-2-FUROIC TOFA;TOFA - CAS 54857-86-2 - Calbiochem
CBNumber:
CB4759746
Summenformel:
C19H32O4
Molgewicht:
324.45
MOL-Datei:
54857-86-2.mol

5-(TETRADECYLOXY)-2-FUROIC ACID Eigenschaften

Schmelzpunkt:
112-115 °C
Siedepunkt:
441.7±25.0 °C(Predicted)
Dichte
1.003±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
DMSO: 2.5 mg/mL
Aggregatzustand
solid
pka
3.55±0.10(Predicted)
Farbe
white to beige
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Sicherheit

WGK Germany  2
RTECS-Nr. LU0288000
HS Code  29321900

5-(TETRADECYLOXY)-2-FUROIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

TOFA has been used as a lipid biosynthesis inhibitor in mesenchymal stromal cells (MSCs), human pluripotent stem cells., an acetyl-CoA carboxylase 1 inhibitor in murine adipocyte cell lines., a lipolysis inhibitor in cancer stem cells (CSCs).

Definition

ChEBI: A member of the class of furans that is 2-furoic acid in which the hydrogen at position 5 is replaced by a tetradecyloxy group.

Biochem/physiol Actions

5-(Tetradecyloxy)-2-furoic acid (TOFA) elicits hypolipidemic?functionality by favoring fatty acid breakdown and at the same time preventing biosynthesis. It induces apoptosis in pancreatic cancer cells and favors tumor suppression.

5-(TETRADECYLOXY)-2-FUROIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5-(TETRADECYLOXY)-2-FUROIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 90)Lieferanten
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54857-86-2()Verwandte Suche:

  • TOFA
  • 5-(tetradecyloxy)-2-furancarboxylicaci
  • 5-tetradecyloxy-2-furonicacid
  • mdl14514
  • RMI-14514
  • TOFA (5-(Tetradecyloxy)-2-furoic acid)
  • 5-(TETRADECYLOXY)-2-FURANCARBOXYLIC ACID
  • 5-(TETRADECYLOXY)-2-FUROIC ACID
  • 2-Furancarboxylic acid,5-(tetradecyloxy)-
  • TOFA (RMI14514
  • TOFA (RMI14514:MDL14514)
  • 5-(TETRADECYLOXY)-2-FUROIC TOFA
  • TOFA - CAS 54857-86-2 - Calbiochem
  • RMI14514; MDL14514
  • inhibit,RMI 14514,Acetyl-CoA Carboxylase,ACC, Acetyl Coenzyme A Carboxylase,RMI-14514,TOFA,MDL 14514,MDL-14514,Inhibitor
  • 54857-86-2
  • A to C
  • Biochemicals and Reagents
  • BioChemical
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • Acetyl CoA-Carboxylase
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