PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Gastrin has been used:

• as a medium supplement establish enteroid cultures
• as a supplement to standard Dulbecco′s Modified Eagle Medium (DMEM) culture medium, human minigut medium to establish the growth of crypts.

Allgemeine Beschreibung

GAST gene encodes for the protein [Leu15]-Gastrin I in human. In human chromosome, the gene GAST is localized on 17q21.2. G cells in the stomach antrum produces the precursor of [Leu15]-Gastrin I, progastrin. Progastrin undergoes cleavage and processing to yield gastrin, which is trophic for the entire gastrointestinal epithelium. Gastrin is essential for the growth of the digestive system and stimulates the production of gastric acid by parietal cells. Gastrin exerts its function through G-protein-coupled receptor called the cholecystokinin (CCK) or CCK-B receptor (CCK-BR). Gastrin release is stimulated by food, especially protein diet and is inhibited by very low pH. Atrophic gastritis, a Helicobacter pylori infection and long-term administration of proton pump inhibitors infection may cause overexpression of gastrin. Gastric adenocarcinoma show high levels of gastrin.

Biochem/physiol Actions

Gastrin I analog with full biological activity and improved stability in aqueous solutions. Leu15 replaces Met15, that is readily oxidized resulting in loss of biological activity.

PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10310	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	1000	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29815	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38460	58

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• H-PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
• [LEU15]-GASTRIN I
• PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
• PGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
• leu(15)-gastrinheptadecapeptid
• 18-(5-Oxo-L-proline)-22-L-leucine-32-L-leucine-18-34-gastrinI【pig】
• 5-Oxo-L-Pro-Gly-L-Pro-L-Trp-L-Leu-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Leu-L-Asp-L-Phe-NH2
• (Leu15)-Gastrin I (huMan) (Leu15)-Gastrin-17 I (huMan), (Pyr18,Leu22,Leu32)-Gastrin I (18-34) (porcine)
• (Leu15)-Gastrin-17 I (huMan), (Pyr18,Leu22,Leu32)-Gastrin I (18-34) (porcine)
• [18-Pyroglutamic acid, 32-leucine]-Big gastrin I-(18-34)-peptide amide, human
• [Leu15]-HG-17
• [Leucine15]-Gastrin I heptadecapeptide
• [Leucine15]-Little gastrin I
• LHG-17
• (Leu15)-Gastrin-17 I (human)
• 18-34-Gastrin I (pig), 18-(5-oxo-l-proline)-22-l-leucine-32-l-leucine-
• [15-leucine]-gastrin i, human heptadecapeptide
• gastrin heptadecapeptide, Leu(15)-
• gastrin I, human Leu15
• [15-leucine]gastrin I, human
• [15-Leucine]-Gastrin I, human heptadecapeptide, [Leu15]-Gastrin I, human, [Leu15]-HG-17, [Leucine15]-Gastrin I heptadecapeptide, [Leucine15]-Little gastrin I, LHG-17, [18-Pyroglutamic acid, 32-leucine]-Big gastrin I-(18-34)-peptide amide, human
• (15-LEUCINE) HUMAN GASTRIN I
• (LEU15)-GASTRIN I (HUMAN)
• L-Phenylalaninamide, 5-oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-leucyl-L-α-aspartyl-
• Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2
• (Leu??)-Gastrin I (human)
• 39024-57-2
• C98H126N20O31
• Gastrins
• Gastrointestinal Products
• Peptides
• BioChemical
• Amino Acids and Peptides
• Biochemicals and Reagents