4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
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- CAS-Nr.
- 59662-49-6
- Englisch Name:
- 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
- Synonyma:
- 8BCA;AC 55649;AC55649,AC 55649;RARECHEM AL BO 1323;4-(4-Octylphenyl)-benzoic acid;4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID;4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID;4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID;4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID;4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
- CBNumber:
- CB4462046
- Summenformel:
- C21H26O2
- Molgewicht:
- 310.43
- MOL-Datei:
- 59662-49-6.mol
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4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Eigenschaften
- Schmelzpunkt:
- 148-152 °C(Solv: dichloromethane (75-09-2))
- Siedepunkt:
- 462.0±34.0 °C(Predicted)
- Dichte
- 1.037±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- L?slichkeit
- DMSO: >7mg/mL
- Aggregatzustand
- solid
- pka
- 4.23±0.10(Predicted)
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H413 |
Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 4 |
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Sicherheit |
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4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
Biologische Aktivit?t
Potent, isoform-selective RAR β 2 receptor agonist (pEC 50 values are 6.9, 5.7 and 5.6 at RAR β 2, RAR β 1 and RAR α respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.
Biochem/physiol Actions
AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.
4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 68)Lieferanten
59662-49-6()Verwandte Suche:
- 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
- 4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID
- 4'-OCTYL-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
- 4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID
- 4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID
- 8BCA
- AC 55649
- 4-(4-Octylphenyl)-benzoic acid
- 4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid
- RARECHEM AL BO 1323
- [1,1'-Biphenyl]-4-carboxylic acid, 4'-octyl-
- AC55649,AC 55649
- 4'-Octyl[1,1'-biphenyl]-4-carboxylic acid
- 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
- 59662-49-6
- Biphenyl & Diphenyl ether