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4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Struktur
59662-49-6
CAS-Nr.
59662-49-6
Englisch Name:
4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
Synonyma:
8BCA;AC 55649;AC55649,AC 55649;RARECHEM AL BO 1323;4-(4-Octylphenyl)-benzoic acid;4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID;4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID;4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID;4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID;4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
CBNumber:
CB4462046
Summenformel:
C21H26O2
Molgewicht:
310.43
MOL-Datei:
59662-49-6.mol

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Eigenschaften

Schmelzpunkt:
148-152 °C(Solv: dichloromethane (75-09-2))
Siedepunkt:
462.0±34.0 °C(Predicted)
Dichte
1.037±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
DMSO: >7mg/mL
Aggregatzustand
solid
pka
4.23±0.10(Predicted)
Farbe
White to off-white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H413 Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 4
Sicherheit

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Potent, isoform-selective RAR β 2 receptor agonist (pEC 50 values are 6.9, 5.7 and 5.6 at RAR β 2, RAR β 1 and RAR α respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.

Biochem/physiol Actions

AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 69)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 31991 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30241 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38460 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18
sales@capotchem.com China 18207 66
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4456 55

59662-49-6()Verwandte Suche:

  • 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
  • 4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID
  • 4'-OCTYL-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
  • 4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID
  • 4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID
  • 8BCA
  • AC 55649
  • 4-(4-Octylphenyl)-benzoic acid
  • 4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid
  • RARECHEM AL BO 1323
  • [1,1'-Biphenyl]-4-carboxylic acid, 4'-octyl-
  • AC55649,AC 55649
  • 4'-Octyl[1,1'-biphenyl]-4-carboxylic acid
  • 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
  • 59662-49-6
  • Biphenyl & Diphenyl ether
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