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KIN1408

KIN1408 Struktur
1903800-11-2
CAS-Nr.
1903800-11-2
Englisch Name:
KIN1408
Synonyma:
KIN1408;KIN-1408 (KIN-1408;KIN1408 >=98% (HPLC);8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-;7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol);KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL
CBNumber:
CB43121111
Summenformel:
C25H19F2N3O3S
Molgewicht:
479.5
MOL-Datei:
1903800-11-2.mol

KIN1408 Eigenschaften

Siedepunkt:
675.6±65.0 °C(Predicted)
Dichte
1.430±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:34.5(Max Conc. mg/mL);71.95(Max Conc. mM)
Aggregatzustand
A solid
pka
4.22±0.50(Predicted)
Farbe
Light yellow to yellow

Sicherheit

KIN1408 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression of the innate immune genes MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA; ). It exhibits concentration-dependent broad-spectrum antiviral activity against dengue virus 2 as well as the influenza A, Ebola, Nipah, and Lassa viruses.

KIN1408 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KIN1408 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4861 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
 3193328036@qq.com China 29767 68
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720
 psaitong@jm-bio.com China 12306 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
 liming@bio-fount.com China 9729 58
DC Chemicals 021-58447131 13564518121
 sales@dcchemicals.com China 9409 58
  • KIN1408
  • 7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol)
  • KIN-1408 (KIN-1408
  • KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL
  • 8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-
  • KIN1408 >=98% (HPLC)
  • 1903800-11-2
  • C25H19F2N3O3S
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