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N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Struktur
1246298-48-5
CAS-Nr.
1246298-48-5
Englisch Name:
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
Synonyma:
20:0(2S-OH) Ceramide;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
CBNumber:
CB42719825
Summenformel:
C38H75NO4
Molgewicht:
610.01
MOL-Datei:
1246298-48-5.mol

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Eigenschaften

Siedepunkt:
739.3±60.0 °C(Predicted)
Dichte
0.939±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
13.26±0.20(Predicted)

Sicherheit

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.

Biochem/physiol Actions

Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity.

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes 		1-516-855-7709
info@creative-enzymes.com United States 8748 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Codow Chemical Co.,Ltd. 18620099427
 amy@howeipharm.com China 17687 55
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961
 cdhxsj@163.com China 14603 60
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125
 tech@zzbioco.com China 12065 58
  • N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
  • 20:0(2S-OH) Ceramide
  • N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE
  • Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
  • N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
  • 1246298-48-5
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