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TetroMycin A

TetroMycin A Struktur
180027-83-2
CAS-Nr.
180027-83-2
Englisch Name:
TetroMycin A
Synonyma:
TetroMycin A;18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-(acetyloxy)-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,6,7,11,12a,14,15,20a-octamethyl-, (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,20aS,20bR)- (9CI)
CBNumber:
CB42703769
Summenformel:
C36H48O6
Molgewicht:
576.763
MOL-Datei:
180027-83-2.mol

TetroMycin A Eigenschaften

Siedepunkt:
684.1±55.0 °C(Predicted)
Dichte
1.17±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
solid
pka
4.50±1.00(Predicted)

Sicherheit

TetroMycin A Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria including MRSA. Limited availability has restricted further investigation of this metabolite in the literature. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

TetroMycin A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


TetroMycin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054
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  • TetroMycin A
  • 18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-(acetyloxy)-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,6,7,11,12a,14,15,20a-octamethyl-, (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,20aS,20bR)- (9CI)
  • 180027-83-2
  • C36H48O6
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