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PSI-7976

PSI-7976 Struktur
1190308-01-0
CAS-Nr.
1190308-01-0
Englisch Name:
PSI-7976
Synonyma:
PSI-7976;SFB-L-ALANITE-MODEL;SFB-L-Alaninate-Model;Sofosbuvir (R)-Phosphate;Sofosbuvir phosphate salt;(R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A);N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate
CBNumber:
CB42685935
Summenformel:
C22H29FN3O9P
Molgewicht:
529.45
MOL-Datei:
1190308-01-0.mol

PSI-7976 Eigenschaften

Schmelzpunkt:
76-82°C
Dichte
1.41±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
pka
9.39±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

PSI-7976 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7976 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


PSI-7976 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 86)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946
sales@huarongpharm.com CHINA 3148 58
sgtlifesciences pvt ltd
+8617013299288
dj@sgtlifesciences.com China 12373 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522
overseasales@yongstandards.com China 11922 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Moxin Chemicals
+8617320513646
mike@molcoo.com China 9447 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
Shanghai Payne Pharmaceutical Technology Co.Ltd
021-58123769 18678586262
info@paynepharm.com China 1354 58

  • PSI-7976
  • N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester
  • Sofosbuvir (R)-Phosphate
  • (S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
  • Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of Sofosbuvir L-alanitate (Mixture of Diasteriomers)
  • SFB-L-Alaninate-Model
  • Sofosbuvir phosphate salt
  • Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
  • isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite
  • L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
  • isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate
  • SFB-L-ALANITE-MODEL
  • (R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A)
  • 1190308-01-0
  • 190308-01-0
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