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LEE011

LEE011 Struktur
1256963-02-6
CAS-Nr.
1256963-02-6
Englisch Name:
LEE011
Synonyma:
Rebosini;Ribociclib(LEE011);4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine;CS-842;LEE011;CDK4-IN-1;CDK4 inhibitor;CDK4/6 inhibitor;LEE011 USP/EP/BP;Ribociclib Free Base
CBNumber:
CB42655411
Summenformel:
C22H29ClN8
Molgewicht:
440.97
MOL-Datei:
1256963-02-6.mol

LEE011 Eigenschaften

Schmelzpunkt:
>180°C (dec.)
Siedepunkt:
679.3±65.0 °C(Predicted)
Dichte
1.31±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
7.57±0.50(Predicted)
Aggregatzustand
Solid
Farbe
Beige

Sicherheit

LEE011 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CDK 4/6 Inhibitor is a part of a group of compounds that exhibits selective inhibitory properties towards Cyclin-Dependent Kinases 4 & 6. These compounds are most commonly used to treat patients with breast cancer.

LEE011 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LEE011 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 124)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156
 sales@sdperfect.com China 294 58
Nanjing Gold Pharmaceutical Technology Co. Ltd. 		025-84209270 15906146951
CHINA 115 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714
 FandaChem@Gmail.com China 9087 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070
product@chemlin.com.cn CHINA 3009 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29880 58
Beijing Yibai Biotechnology Co., Ltd 		0086-182-6772-3597
sales04@yibaibiotech.com CHINA 419 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
Echemi Group 		86-18905328650 18905328650
 pharma@echemi.com CHINA 215 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
  • LEE011
  • CDK4/6 inhibitor
  • CDK4 inhibitor
  • CDK4-IN-1
  • CDK 4/6 Inhibitor, >=98%
  • Ribociclib(Lee011 & CDK 4/6 inhibitor)
  • 4-[5-Chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-2-pyrimidinamine
  • 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
  • Ribociclib Free Base
  • 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)py
  • CS-842
  • 2-Pyrimidinamine, 4-[3-chloro-5-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-
  • LEE011 USP/EP/BP
  • 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine
  • Ribociclib(LEE011)
  • Rebosini
  • 1256963-02-6
  • C22H29ClN8
  • Inhibitors
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