CAY10618 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide mononucleotide (NMN), which is subsequently converted to NAD⁺ by NMN adenyltransferase. Cancer cells commonly have an unusually high rate of NAD⁺ turnover, suggesting that inhibition of Nampt might selectively target cancer cells. GPP 78 is a potent inhibitor of Nampt (IC₅₀ = 3 nM). It induces cell death in the neuroblastoma cell line SH-SY5Y with an IC₅₀ value of 3.8 nM through a process that appears to involve autophagy.

CAY10618 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CAY10618 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12306	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Chengdu Peter-like Biotechnology Co., Ltd.	028-81700200 18108052721	2850505130@qq.com	China	5173	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29774	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58

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• CAY10618
• 1H-1,2,3-Triazole-1-octanaMide, N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-
• GPP 78
• CAY10618 Exclusive
• N-(2-phenylphenyl)-8-(4-pyridin-3-yltriazol-1-yl)octanamide
• GPP78,GPP-78
• 1202580-59-3