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ALK

ALK Struktur
CAS-Nr.
Englisch Name:
ALK
Synonyma:
ALK;Recombinant Human CD246/ALK Protein, His Tag
CBNumber:
CB42541446
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ALK Eigenschaften

Sicherheit

ALK Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded by the ALK gene.

Biologische Funktion

The receptor ALK plays a pivotal role in cellular communication and in the normal development and function of the nervous system.This observation is based on the extensive expression of ALK messenger RNA (mRNA) throughout the nervous system during mouse embryogenesis.In vitro functional studies have demonstrated that ALK activation promotes neuronal differentiation of PC12 or neuroblastoma cell lines.ALK is critical for embryonic development in Drosophila. Flies lacking the receptor die due to failure of founder cell specification in embryonic visceral muscle.However, while ALK knockout mice exhibit defects in neurogenesis and testosterone production, they remain viable, suggesting that ALK is not critical to their developmental processes.

Toxikologie

The ALK gene can be oncogenic in three ways – by forming a fusion gene with any of several other genes, by gaining additional gene copies or with mutations of the actual DNA code for the gene itself.

ALK Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ALK Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10424 58
Shanghai Universal Biotech Co.,Ltd 13774214275
zhouzz@univ-bio.com China 24994 58
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058
yajikit@163.com China 9670 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749
sales@shzbio.com China 9966 58

  • ALK
  • Recombinant Human CD246/ALK Protein, His Tag
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