(5α,12R,19α)-2,3-Didehydro-6α,7α-epoxyaspidospermidine-3-carboxylic acid methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
One of the numerous alkaloids which have been isolated from Vinca rosea L.
(Syn. Catharanthus roseus G. Don.), this base yields colourless crystals from
MeOH and is strongly laevorotatory with [α]
D - 528° (CHCl3) or [α]
27D - 432°
(CHCI3). The ultraviolet spectrum of the alkaloid in EtOH shows three absorption maxima at 226, 297 and 327 ffi/.l. The suggested structure contains one
methoxycarbonyl group, an imino group, a bridge ethyl group and an epoxy
ring. The second nitrogen atom is tertiary.
Einzelnachweise
Nair, Pillay., Tetrahedron, 6,89 (1959)
Gorman et at., J. Amer. Pharm. Assoc., Sci. Ed., 48, 256 (1959)
Moza, Trojanck., Chem. Ind., 1425 (1962)
Mozaetat., Tetrahedron Lett., 2561 (1964)
(5α,12R,19α)-2,3-Didehydro-6α,7α-epoxyaspidospermidine-3-carboxylic acid methyl ester Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte