5-Methoxyuridin
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- CAS-Nr.
- 35542-01-9
- Bezeichnung:
- 5-Methoxyuridin
- Englisch Name:
- 5-METHOXYURIDINE
- Synonyma:
- 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione;mo(5)U;5-METHOXYURIDINE;5-MethoxyuridineA;Uridine, 5-methoxy-;5 –Methoxyuridine,RNA anticodon nucleoside for RNA vaccines and geno mics,P2Y6 receptor agonist;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
- CBNumber:
- CB4144845
- Summenformel:
- C10H14N2O7
- Molgewicht:
- 274.23
- MOL-Datei:
- 35542-01-9.mol
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5-Methoxyuridin Eigenschaften
- Dichte
- 1.65±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- 8?+-.0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- maximale Wellenl?nge (λmax)
- 279 (pH 2)；277 (pH 12)
5-Methoxyuridin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Solid
Verwenden
5-Methoxyuridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.
Definition
ChEBI: A derivative of uridine, bearing an additional methoxy substituent at position 5 on the uracil ring.
Synthese
5-Hydroxyuridine was synthesized by the method described by T. Ueda. 5-Hydroxyuridine (30 mg) was further methylated by 20 y1 of dimethyl sulfate in 0.6 ml of 0.1 N NaOH. A reaction mixture was chromatographed on Whatman 3MM paper using solvent D. The band containing 5-Hydroxyuridine was extracted with water and the extract was further purified by paper chromatography in sol vent E. These procedures gave a 25% yield of mo5l). In addition to 5-Hydroxyuridine and the raw material, the methylated products contained 5% of 5-hydroxy-3-methyl uridine and 4% of 5-methoxy-3-methyluridine.
5-Methoxyuridin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Methoxyuridin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 82)Lieferanten
35542-01-9(5-Methoxyuridin)Verwandte Suche:
- 5-METHOXYURIDINE
- mo(5)U
- Uridine, 5-methoxy-
- 5 –Methoxyuridine,RNA anticodon nucleoside for RNA vaccines and geno mics,P2Y6 receptor agonist
- 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione
- 5-MethoxyuridineA
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 35542-01-9
- C10H14N2O7
- Nucleoside Analogs
- Nucleosides, Nucleotides, Oligonucleotides
- Biochemicals and Reagents
- BioChemical
- Biochemicals and Reagents
- Nucleoside Analogs
- Nucleosides, Nucleotides, Oligonucleotides
