α-Hydroxy-β,β-dimethyl-γ-butyrolacton
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- CAS-Nr.
- 599-04-2
- Bezeichnung:
- α-Hydroxy-β,β-dimethyl-γ-butyrolacton
- Englisch Name:
- D-(-)-PANTOLACTONE
- Synonyma:
- PANTOLACTONE;D-PANTOLACTONE;(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one;Pantoyl lactone;Pantoyllactone;(R)-(-)-PANTOLACTONE;Dexpanthenol Lactone IMpurity;(3R)-3-hydroxy-4,4-dimethyloxolan-2-one;2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-;Pantolacton
- CBNumber:
- CB3748921
- Summenformel:
- C6H10O3
- Molgewicht:
- 130.14
- MOL-Datei:
- 599-04-2.mol
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α-Hydroxy-β,β-dimethyl-γ-butyrolacton Eigenschaften
- Schmelzpunkt:
- 91 °C(lit.)
- Siedepunkt:
- 120-122 °C15 mm Hg(lit.)
- Dichte
- 1.1066 (rough estimate)
- Dampfdruck
- 0.3-3.28Pa at 15-35℃
- Brechungsindex
- -50.8 ° (C=2, H2O)
- Flammpunkt:
- 120-122°C/15mm
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly)
- pka
- 13.12±0.40(Predicted)
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- White
- Geruch (Odor)
- cotton candy
- Optische Aktivit?t
- [α]25/D 49.8°, c = 2 in H2O
- Wasserl?slichkeit
- almost transparency
- Sensitive
- Hygroscopic
- Merck
- 14,7013
- BRN
- 80957
- InChIKey
- SERHXTVXHNVDKA-BYPYZUCNSA-N
- LogP
- -0.973--0.46 at 22.5-25℃ and pH7.1
- CAS Datenbank
- 599-04-2(CAS DataBase Reference)
- EPA chemische Informationen
- Pantolactone (599-04-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
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| WGK Germany |
1 |
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| F |
3-10 |
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| TSCA |
Yes |
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| HS Code |
29322090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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α-Hydroxy-β,β-dimethyl-γ-butyrolacton Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
WHITE CRYSTALLINE POWDER OR CRYSTALS
Verwenden
D-(-)-PANTOLACTONE is an important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
l?uterung methode
Recrystallise the lactone from Et2O/pet ether, diisopropyl ether or *C6H6/pet ether and sublime it at 25o/0.0001mm. It hydrolyses readily to the hydroxy-acid and racemises when heated above 145o. The Brucine salt has m 211-212o (from EtOH). [Kuhn & Wieland Chem Ber 73 1134 1940, and Stiller et al. J Am Chem Soc 62 1779 1940, Bental & Tishler J Am Chem Soc 68 1463 1946, Beilstein 18/1 V 22.]
α-Hydroxy-β,β-dimethyl-γ-butyrolacton Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
α-Hydroxy-β,β-dimethyl-γ-butyrolacton Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 330)Lieferanten
599-04-2(α-Hydroxy-β,β-dimethyl-γ-butyrolacton)Verwandte Suche:
- (R)-()-β,β-Dimethyl-α-hydroxy-γ-butyrolactone
- (R)-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
- (R)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
- (R)-(-)-BETA,BETA-DIMETHYL-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
- (R)-(-)-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
- R(-)-3,3-DIMETHYL-2-HYDROXY-GAMMA-BUTYROLACTONE
- R(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
- PANTOIC ACID GAMMA-LACTONE
- PANTOLACTONE-D
- 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, D-(-)-
- 4-dimethyl-dihydro-3-hydroxy-(theta)-2(3h)-furanon
- D-(-)-Pantoic acid lactone
- D-(-)-Pantolyl lactone
- dihydro-3-hydroxy-4,4-dimethyl-,(R)-2(3H)-Furanone
- Dihydro-4,4-dimethyl-3-hydroxy-2(3H)-furanone
- -Hydroxy-,-dimethyl-butyrolactone
- Pantoiclactone
- Pantolyl lactone
- Pantothenic lactone
- Pentoyl lactone
- Pentoyl lactone clene
- D-()-Pantolactone,(R)-()-α-Hydroxy-β,β-dimethyl-γ-butyrolactone, (R)-()-β,β-Dimethyl-α-hydroxy-γ-butyrolactone, (R)-()-Pantolactone, Pantoic acid γ-lactone
- Pan-acid lactone
- (-)-2-Hydroxy-3,3-diMethyl-γ-butyrolactone
- (3R)-Dihydro-3-hydroxy-4,4-diMethyl-2(3H)-furanone
- (3R)-Tetrahydro-3-hydroxy-4,4-diMethylfuran-2-one
- (R)-(-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
D-(-)-2-Hydroxy-3,3-dimethyl-gamma-butyrolactone
D-(-)-Pantoyl Lactone
- Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
- D-(-)-Pantolactone 99%
- (R)-Pantolacton
- 2,4-DIHYDROXY-3,3-DIMETHYLBUTYRIC ACID GAMMA-LACTONE
- ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
- D-(-)-PANTOYL LACTONE
- D-PANTOYL LACTONE
- D-PANTOIC ACID G-LACTONE
- (-)-D-PANTOLACTONE
- D-(-)-PANTOLACTONE
- D-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
- D-1-HYDROXY-2,2-DIMETHYL-3-BUTYROLACTONE
- D-(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
- D-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
- (R)-N-Pantolactone
- (R)-Pantoyl lactone
- alpha-Hydroxy-beta,beta-dimethyl-alpha-butyrolactone
- D-MINUS-PANTOYLLACTONE
- D-(-)-PANTOYL LACTONE 98+%
- D-(-)-Pantanolactone
- D-(-)-Pantolactone,99%
- pantolactone,dihydro-3-hydroxy-4,4-dimethyl-2(3H)-Furanone,Pantoyllactone
- alpha-Hydroxy-beta,beta-dimeth
- 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (3R)-
- (r)-(-)-α-hydroxy-β,β-dimethyl-γ-butyrolactone
- Pantolacton
- (R)-(-)-Pantolactone, Pantoic acid γ-lactone, (R)-(-)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone, (R)-(-)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone
- (R)-4,5-Dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one
- [R,(-)]-3-Hydroxy-4,4-dimethyl-4,5-dihydrofuran-2(3H)-one
- Pantolactone (500 mg)
- Dexpanthenol Impurity 1
