THIOLUTIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R28:Sehr giftig beim Verschlucken.

S-S?tze Betriebsanweisung:

S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Beschreibung

Thiolutin is a natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases (IC₅₀ = 3 μg/ml). Because of this, it can be used for the analysis of mRNA stability. Thiolutin also inhibits endothelial cell adhesion (IC₅₀ < 1 μM) and S180 tumor-induced angiogenesis in mice by inhibiting Hsp27 interactions with cytoskeletal elements.

Chemische Eigenschaften

Yellow solid

Verwenden

Thiolutin is an antibiotic isolated from several strains of Streptomyces albus. Thiolutin is a natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases.

Biologische Aktivit?t

Antibiotic; inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC 50 = 0.83 mM) and subsequently reduces paxillin levels. Suppresses tumor cell-induced angiogenesis.

Sicherheitsprofil

Poison by ingestion andsubcutaneous routes. When heated to decomposition itemits very toxic fumes of NOx and SOx.

THIOLUTIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

THIOLUTIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22784	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60

87-11-6()Verwandte Suche:

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• acetopyrrothine
• 6-acetamido-4-methyl-2-dithiolo(4.3-b)pyrrol-5(4h)-one
• 6-acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4h)-one
• 6-(acetylamino)-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4h)-one
• N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
• N-(4-methyl-5-oxo-[1,2]dithiolo[4,3-b]pyrrol-6-yl)ethanamide
• T-00098
• 4-Methyl-6-(acetylamino)-4,5-dihydro-1,2-dithiolo[4,3-b]pyrrole-5-one
• 4-Methyl-6-(acetylamino)-1,2-dithiolo[4,3-b]pyrrole-5(4H)-one
• Thiolutin from Streptomyces luteosporeus
• Aureothricin, Farcinicin, Propiopyvothine
• 6-acetamido-4-methyl-1,2-dithiolo[4,3-b]pyrrol-5-one
• Thiolutin NSC 3927
• NSC 3927
• Acetopyrrothin
• Thiolutin ,80%
• N-(5-keto-4-methyl-dithiolo[4,3-b]pyrrol-6-yl)acetamide
• N-acetylpyrrothine, Farcinicine, Acetopyrrothine
• N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetaMide
• 3-acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole
• N-(4,5-DIHYDRO-4-METHYL-5-OXO-1,2-DITHIOLO[4,3-B]PYRROL-6-YL)ACETAMIDE
• THIOLUTIN
• THIOLUTIN USP/EP/BP
• Thiolutin, from Streptomyces
• Acetamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-
• THIOLUTIN (ACETOPYRROTHIN)
• 87-11-6
• 1987-11-6
• C8H8N2S2O2
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