FELBAMATE-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Felbamate-d₄ is intended for use as an internal standard for the quantification of felbamate by GC- or LC-MS. Felbamate is an inhibitor of NMDA receptors and a modulator of GABA_A receptors that also has broad-spectrum inhibitory activity against excitatory amino acid receptors. It binds to NMDA channels with dissociation constants of approximately 200, 110, and 55 μM in the resting, activated, and desensitized states, respectively, and inhibits NMDA currents in a use-dependent manner. Felbamate is a positive modulator of α₁β₂γ_2S, α₁β₃γ_2S, α₂β₂γ_2S, and α₂β₃γ_2S subunit-containing GABA_A receptors expressed in X. laevis oocytes, with negative modulation of GABA_A receptors containing the subunits α₁β₁, α₁β₃γ_2L, α₄β₁γ_2S, α₄β₃γ_2S, and α₆β₁γ_2S. It inhibits seizures induced by maximal electroshock, pentylenetetrazole , and picrotoxin in mice (ED₅₀s = 16.3, 5.51, and 5.23 mg/kg, respectively). Formulations containing felbamate have been used in the treatment of severe refractory seizures.

Chemische Eigenschaften

White Solid

FELBAMATE-D4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FELBAMATE-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Guangzhou PI PI Biotech Inc	020-81716320 +86-13602409664	Sales@pipitech.com	China	3633	55
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9679	58
Cato Research Chemicals Inc.	020-81960175	min.he@cato-chem.com	China	1955	55
Shanghai Champ Biopharmaceuticals Co., Ltd.	021-61537865 13585780846	sales@champchem.com	China	360	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57423	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Manhag Testing Technology Co., Ltd	020-020-3846236 17688849268	2443244976@qq.com	China	7775	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-021-61109150	sales@tcisct.com	China	31121	58

106817-52-1()Verwandte Suche:

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• 2-Phenyl-1,3-propanedioldicarbamate-d4
• ADD-03055-d4
• Carbamic Acid 2-Phenyltrimethylene-d4 Ester
• Felbamyl-d4
• Felbatol-d4
• Taloxa-d4
• W-554-d4
• FELBAMATE-D4
• 2-Phenyl-(1,1,3,3-tetra-deuterio)-1,3-propanediol Dicarbamate
• WKGXYQFOCVYPAC-KXGHAPEVSA-N
• Felbamate D4Q: What is Felbamate D4 Q: What is the CAS Number of Felbamate D4 Q: What is the storage condition of Felbamate D4 Q: What are the applications of Felbamate D4
• 106817-52-1
• C11H10D4N2O4
• Pharmaceuticals
• Isotope Labelled Compounds
• Intermediates & Fine Chemicals
• Isotope Labeled Compounds