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Nitrefazol

Nitrefazole Struktur
21721-92-6
CAS-Nr.
21721-92-6
Bezeichnung:
Nitrefazol
Englisch Name:
Nitrefazole
Synonyma:
bt-985;ALTIMOL;EMD 15700;NITREFAZOLE;1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE;2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol;2-methyl-4-nitro-1-(4-nitrophenyl)imidazole;2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol;2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole;1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
CBNumber:
CB3356045
Summenformel:
C10H8N4O4
Molgewicht:
248.19
MOL-Datei:
21721-92-6.mol

Nitrefazol Eigenschaften

Schmelzpunkt:
185-187°
storage temp. 
Refrigerator
L?slichkeit
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
Farbe
Light Yellow to Yellow

Sicherheit

Nitrefazol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Nitrefazole is an inhibitor of aldehyde dehydrogenase useful in the management of alcoholism. Cited advantages over disulfiram include longer duration of action, higher specificity (no inhibition of dopamine β-hydroxylase) and fewer side effects. It is generally recognized that the efficacy of such agents with respect to permanent abstinence is low. However, temporary abstinence and/or controlled drinking may facilitate supportive psychotherapy and/or delay the onset of severe alcoholic diseases.

Verwenden

Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.

Weltgesundheitsorganisation (WHO)

Nitrefazole, which is used in the treatment of alcoholism, was introduced in the early 1980s. By 1984 its use had been associated with hepatotoxic reactions, some of which were fatal. This led to its withdrawal in at least two countries. WHO has no information to suggest that preparations containing nitrefazole remain commercially available.

Nitrefazol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Nitrefazol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 13)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894
shawn@hirisunpharm.com CHINA 9911 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19863 58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291
tcy@tcypharm.com China 5595 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44808 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24648 58
Dongyang Qiusuo Medical Technology Co., LTD 17502510579
2785299132@qq.com China 1558 58

21721-92-6(Nitrefazol)Verwandte Suche:


  • ALTIMOL
  • 1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE
  • EMD 15700
  • 2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol
  • 2-methyl-4-nitro-1-(4-nitrophenyl)imidazole
  • 2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol
  • bt-985
  • NITREFAZOLE
  • 2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole
  • 1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
  • 21721-92-6
  • C10H8N4O4
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