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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Struktur
21561-09-1
CAS-Nr.
21561-09-1
Englisch Name:
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Synonyma:
WHI-P258;JAK3 INHIBITOR, NEGATIVE CONTROL;4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE;6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE;6,7-dimethoxy-N-phenylquinazolin-4-amine;4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-;N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE;JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258;WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
CBNumber:
CB3348071
Summenformel:
C16H15N3O2
Molgewicht:
281.31
MOL-Datei:
Mol file

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Eigenschaften

Siedepunkt:
441.2±40.0 °C(Predicted)
Dichte
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
Aggregatzustand
A crystalline solid
pka
6.19±0.70(Predicted)
Farbe
White to off-white

Sicherheit

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.

Verwenden

4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 70)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32112 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30242 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
  • WHI-P258
  • 4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-
  • N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE
  • 6,7-dimethoxy-N-phenylquinazolin-4-amine
  • JAK3 INHIBITOR, NEGATIVE CONTROL
  • 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
  • 6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE
  • JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258
  • WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
  • 21561-09-1
  • Inhibitors
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