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2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-

DIGITONIN Struktur
11024-24-1
CAS-Nr.
11024-24-1
Bezeichnung:
2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-
Englisch Name:
DIGITONIN
Synonyma:
itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONINE AR
CBNumber:
CB3331307
Summenformel:
C56H92O29
Molgewicht:
1229.31
MOL-Datei:
11024-24-1.mol

2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Eigenschaften

Schmelzpunkt:
230-240 °C (dec.)(lit.)
Siedepunkt:
788.4°C (rough estimate)
alpha 
D20 -54° (0.45 g in 15.8 ml methanol)
Dichte
1.1421 (rough estimate)
Brechungsindex
-52 ° (C=1, EtOH)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
H2O: 10 mg/mL at 95 °C hot, clear, colorless
Aggregatzustand
White powder
pka
12.68±0.70(Predicted)
Farbe
white
Optische Aktivit?t
[α]20/D 54°, c = 2.8 in methanol(lit.)
Biologische Quelle
plant seeds (Digitalis purpurea)
Wasserl?slichkeit
H2O: ~5% (w/v) (solubilized by heating to 95 °C - 98 °C and then cooling to room temp.)
Merck 
14,3161
BRN 
78654
Stabilit?t:
Hygroscopic
InChIKey
FAAZZWIYYDUONB-JYIJKGCVSA-N
EPA chemische Informationen
Digitonin (11024-24-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 23/24/25
S-S?tze: 22-28-36/37-45
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS-Nr. IH2050050
3-10
HazardClass  6.1(a)
PackingGroup  II
HS Code  29389090
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
H373 Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P314 Bei Unwohlsein ?rztlichen Rat einholen / ?rztliche Hilfe hinzuziehen.

2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Chemische Eigenschaften

white crystalline powder

Verwenden

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

Allgemeine Beschreibung

Crystals or white powder.

Air & Water Reaktionen

Forms soapy aqueous suspension .

Reaktivit?t anzeigen

DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992

Brandgefahr

Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.

Sicherheitsprofil

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.

l?uterung methode

This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]

2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 303)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20267 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29879 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58

11024-24-1(2,15-Dihydroxyspirostan-3-yl-O-beta-D-glucopyrasonyl-(1-3)-O-D-galactopyranosyl-(1-2)O-(beta-D-xylo-pyranosyl-(1-3)-O-beta-D-glucopyranosyl-(1-4)-beta-D-galyctopyranosid, (2 alpha,3 beta, 5 alpha, 15 beta, 25R)-)Verwandte Suche:


  • 25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE
  • DIGITONIN CRYSTALLINE
  • Digitonin, High Purity
  • DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING
  • DigitoninGr
  • Digitonin, AR
  • DIGITONIN, USED AS NON-IONIC DETERGE
  • beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)-
  • (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside
  • DIGITONIN TECH
  • DIGITONIN,CRYSTAL,REAGENT
  • DIGITONIN(RG)
  • (1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D-
  • (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside
  • beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd
  • osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos
  • roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran
  • yl-(1.fwdarw.4)-
  • Digitonin ,50%
  • 2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside
  • DIGITIN
  • DIGITONIN
  • DIGITONIN, ALCOHOL-SOLUBLE
  • DIGITONIN WATER SOLUBLE
  • Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-
  • galactopyranoside]
  • Digitonin, approx. 50% (TLC)
  • [(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside
  • Digitonin, approx. 50% (TLC) 500MG
  • Digitonin, approx. 50% (TLC) 5GR
  • DIGITONINANALYTICAL GRADE
  • DIGITONIN WATER SOLUBLERESEARCH GRADE
  • Digitonin,Digitin
  • Digitonin, approx. 50%, water soluble
  • 5% Digitonin
  • Digitonin USP
  • itonin
  • β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-
  • Digitonin (Digitin) extrapure, 50%
  • 3-Benzoxazole-6-carboxylic acid
  • igitonin
  • Digitonin (8CI)
  • Digitonin 99% AR
  • DIGITONINE AR
  • Digitonin, detergent for solubilizing receptors and cellular membranes
  • 11024-24-1
  • C56H92O29
  • C56H92O28
  • Sterols
  • Lipids
  • Non-Ionic
  • Detergents
  • Conjugates
  • Biochemicals and Reagents
  • BioChemical
  • Surfactants (for Biochemistry)
  • Sugars
  • Nonionic Surfactants (for Biochemistry)
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