Shikalkin
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- CAS-Nr.
- 54952-43-1
- Englisch Name:
- Shikalkin
- Synonyma:
- shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
- CBNumber:
- CB3273506
- Summenformel:
- C16H16O5
- Molgewicht:
- 288.3
- MOL-Datei:
- 54952-43-1.mol
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Shikalkin Eigenschaften
- Schmelzpunkt:
- 144-145 °C
- Siedepunkt:
- 567.4±50.0 °C(Predicted)
- Dichte
- 1.373±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- methanol: soluble1mg/mL
- pka
- 7.34±0.20(Predicted)
- Aggregatzustand
- powder or solid
- Farbe
- red to brown
- LogP
- 4.350 (est)
Shikalkin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Shikonin has been used:
- to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
- as an inhibitor of renal aerobic glycosis and a potential
- as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
- to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death
Allgemeine Beschreibung
Shikonin is a major phytochemical compound extracted from the roots of
Lithospermum erythrorhizon. It is a natural anthraquinone derivative.
Biochem/physiol Actions
Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.
Shikalkin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Shikalkin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 68)Lieferanten
54952-43-1()Verwandte Suche:
- 5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione
- SHIKALKIN
- 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci)
- Arnebin-4
- Nsc 291845
- shiconin
- Shikonin (mixture of optical isomers, about 1:1)
- 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)-
- Shikonin >=98% (HPLC)
- (+-)-Shikonin
- (Rac)-Shikonin
- 5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
- Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin
- 54952-43-1
- Inhibitors
- Coronavirus
