DBCO-amine
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- CAS-Nr.
- 1255942-06-3
- Englisch Name:
- DBCO-amine
- Synonyma:
- DBCO-NH2;DBCO-amine;DBCO-CH2CH2NH2;DBCO-(CH2)2-NH2;ADIBO-CH2CH2NH2·TFA;DBCO-(CH2)3-NH2.TFA;DBCO-(CH2)2-NH2.TFA;Azadibenzocyctenylamine;Dibenzocyclooctyne-amine;DBCO-Amine
(DBCO amine)
- CBNumber:
- CB32730210
- Summenformel:
- C18H16N2O
- Molgewicht:
- 276.33
- MOL-Datei:
- 1255942-06-3.mol
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DBCO-amine Eigenschaften
- Schmelzpunkt:
- 86-96°C
- Siedepunkt:
- 549.9±50.0 °C(Predicted)
- Dichte
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 8.81±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Yellow to Orange
- InChI
- InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2
- InChIKey
- PQFQVUMDOWUGMK-CHMOPDDRSA-N
- SMILES
- C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCN
DBCO-amine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
Properties and Applications
DBCO-amine is an aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition (SPAAC, also known as “copper-free click chemistry”). The DBCO moiety reacts selectively with azides via SPAAC to form stable triazole linkages. The amine terminus of the molecule reacts with carboxylic acids and their active esters to form stable amide bonds. Insoluble in water, DBCO-amine is slightly soluble to sparingly soluble in most organic solvents. It recommends dimethylsulfoxide (DMSO), N, N’-dimethylformamide (DMF), or N, N’-dimethylacetamide (DMAC) as solvents for this product. DBCO-amine is relatively insensitive to bases and can be used in the presence of aqueous bases. This product is acid-sensitive. It should not be subjected to pH <5 during reaction or workup. The product should always be stored at -20°C when not in use.
DBCO-amine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
DBCO-amine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 170)Lieferanten
1255942-06-3()Verwandte Suche:
- Dibenzocyclooctyne-aMine for Copper-free Click CheMistry
- ADIBO-CH2CH2NH2·TFA
- Azadibenzocyclooctyne-(CH2)2-amine TFA
- Dibenzocyclooctyne-amine
- DBCO-(CH2)2-NH2.TFA
- DBCO-(CH2)3-NH2.TFA
- DBCO-(CH2)2-NH2
- Azadibenzocyclooctyne-amine
- Dibenzocyclooctyne-amine (This product is unavailable in the U.S.)
- 1-Propanone, 3-amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-
- 3-amino-1-{2-azatricyclo[10.4.0.0?,?]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}propan-1-one
- DBCO-Amine
(DBCO amine)
- Azadibenzocylooctyne-amine
- 3-Amino-1-[(5-aza-3,4:7,8-dibenzocyclooct-1-yne)-5-yl]-1-propanone
- 3-Amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone
- DBCO-amine
- DBCO-NH2
- 1-Propanone, 3-amino-1-(11,12-didehydrodibenz[b,?f]azocin-5(6H)-yl)- （DBCO-NH2）
- ADC,Antibody-drug conjugates linkers,inhibit,non-cleavable,ADC Linkers,Inhibitor,DBCOamine,antibody-drug,DBCO-amine,conjugates,DBCO amine
- DBCO-CH2CH2NH2
- 3-amino-1-{10-azatricyclo[10.4.0.04,9]hexadeca-1(16),4(5),6,8,12(13),14-hexaen-2-yn-10-yl}propan-1-one
- 3-amino-1-(2-azatricyclo[10.4.0.0^{4,9}]hexadeca-1(12),4,6,8,13,15-hexaen-10-yn-2-yl)propan-1-one
- Azadibenzocyctenylamine
- 1255942-06-3
- DBCO
