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1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- Struktur
509102-00-5
CAS-Nr.
509102-00-5
Englisch Name:
1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-
Synonyma:
MIM1;CS-1192;MIM 1;MIM-1;Inhibitor of Mcl-1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-;4-[[[2-(Cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol;inhibit,Bcl-2 Family,Inhibitor of Mcl1,Inhibitor,MIM-1,MIM1,MIM 1,Inhibitor of Mcl 1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-
CBNumber:
CB32652150
Summenformel:
C17H21N3O3S
Molgewicht:
347.43
MOL-Datei:
509102-00-5.mol

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- Eigenschaften

Siedepunkt:
559.6±60.0 °C(Predicted)
Dichte
1.40±0.1 g/cm3(Predicted)
L?slichkeit
insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL in DMSO
Aggregatzustand
A crystalline solid
pka
7.73±0.45(Predicted)
Farbe
White to off-white

Sicherheit

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein with a role in cancer. It selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains (IC50 = 4.7 μM). MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.

Verwenden

MIM1 binds to MCL-1 and aids in the modulation of cell death, division and differentiation. MIM1 may be used for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders.

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 54)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
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TargetMol Chemicals Inc.
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Aladdin Scientific 		+1-+1(833)-552-7181
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Amadis Chemical Company Limited 		571-89925085
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MedChemexpress LLC 021-58955995
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EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921
sales@pharmacodia.com China 2317 55

509102-00-5()Verwandte Suche:

  • MIM1
  • 4-[[[2-(Cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol
  • 1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-
  • MIM 1;MIM-1
  • CS-1192
  • Inhibitor of Mcl-1
  • 1,2,3-Benzenetriol, 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-
  • inhibit,Bcl-2 Family,Inhibitor of Mcl1,Inhibitor,MIM-1,MIM1,MIM 1,Inhibitor of Mcl 1
  • 509102-00-5
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