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Glutaminase C-IN-1

Glutaminase C-IN-1 Struktur
311795-38-7
CAS-Nr.
311795-38-7
Englisch Name:
Glutaminase C-IN-1
Synonyma:
CS-2083;GLS-IN-968;Compound 968;GAC Inhibitor 968;Glutaminase C-IN-1;Glutaminase C-IN-1 (968);Glutaminase C inhibitor 1;glutaminase inhibitor 968;Glutaminase Inhibitor Compound 968;Glutaminase Inhibitor 968 >=98% (HPLC)
CBNumber:
CB32561506
Summenformel:
C27H27BrN2O
Molgewicht:
475.42
MOL-Datei:
311795-38-7.mol

Glutaminase C-IN-1 Eigenschaften

Siedepunkt:
623.2±55.0 °C(Predicted)
Dichte
1.39±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
Soluble in DMSO (up to 11 mg/ml) or in Ethanol (up to 1 mg/ml with warming)
pka
4.09±0.42(Predicted)
Aggregatzustand
powder
Farbe
white to beige
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Sicherheit

Glutaminase C-IN-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Glutaminase inhibitor 968 has been used to study the role of glutamine metabolism in macrophage activation.

Allgemeine Beschreibung

Glutaminase Inhibitor 968 belongs to the benzophenanthridinone family.

Biochem/physiol Actions

Glutaminase Inhibitor 968 is an allosteric inihibitor of the mitochondrial enzyme glutaminase C (GAC), which is overexpressed in a number of cancer cell lines. Glutaminase Inhibitor 968 shows 21% inhibition at 10 μM, 94% at 25 μM. Glutaminase Inhibitor 968 blocked human cancer cell proliferation in culture, and in inhibited tumor formation in mouse xenograft models.

Glutaminase C-IN-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Glutaminase C-IN-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 55)Lieferanten
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career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29880 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +8613336024896
 CB@aromsyn.com China 19183 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Beijing HwrkChemical Technology Co., Ltd 010-89508211 18501085097
 sales.bj@hwrkchemical.com China 8418 55
Nanjing Chemlin Chemical Co., Ltd 025-83697070
info@chemlin.com.cn China 19182 64
  • 5-[3-BroMo-4-(diMethylaMino)phenyl]-2,3,5,6-tetrahydro-2,2-diMethylbenzo[a]phenanthridin-4(1H)-one
  • Glutaminase C-IN-1
  • Glutaminase C-IN-1 (968)
  • Glutaminase Inhibitor Compound 968
  • glutaminase inhibitor 968
  • CS-2083
  • 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one
  • Glutaminase C inhibitor 1
  • Compound 968
  • Benzo[a]phenanthridin-4(1H)-one, 5-[3-bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethyl-
  • Glutaminase Inhibitor 968 >=98% (HPLC)
  • GLS-IN-968
  • GAC Inhibitor 968
  • Compound968,Glutaminase,Glutaminase CIN1,Glutaminase C IN 1,Compound-968,inhibit,Inhibitor
  • 311795-38-7
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