2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
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- CAS-Nr.
- 937807-66-4
- Englisch Name:
- 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
- Synonyma:
- Neurodazine;Neurodazine, 10 mM in DMSO;Neurodazine, Induces neurogenesis in skeletal muscle cells;2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole;1H-Imidazole, 2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-;2-[5-(3-Chloro-phenyl)-furan-2-yl]-4,5-bis-(4-methoxy-phenyl)-1H-imidazole
- CBNumber:
- CB32518979
- Summenformel:
- C27H21ClN2O3
- Molgewicht:
- 456.92
- MOL-Datei:
- 937807-66-4.mol
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2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole Eigenschaften
- Siedepunkt:
- 661.4±55.0 °C(Predicted)
- Dichte
- 1.252±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: >20mg/mL
- Aggregatzustand
- powder, yellow
- pka
- 12.84±0.10(Predicted)
- Farbe
- Beige
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Neurodazine induces neurogenesis in mature skeletal muscle cells, via non-pluripotent C2C12 myoblasts.
Allgemeine Beschreibung
A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 μM for 7-10 days). Shown to preferentially upregulate genes involved in neurogenesis, but not those pertaining to myogenesis, in C2C12 myoblasts.
Biochem/physiol Actions
Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 39)Lieferanten
937807-66-4()Verwandte Suche:
- 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
- Neurodazine
- 2-[5-(3-Chloro-phenyl)-furan-2-yl]-4,5-bis-(4-methoxy-phenyl)-1H-imidazole
- 1H-Imidazole, 2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-
- Neurodazine, Induces neurogenesis in skeletal muscle cells
- Neurodazine, 10 mM in DMSO
- 937807-66-4
