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(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium

(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium Struktur
6801-39-4
CAS-Nr.
6801-39-4
Englisch Name:
(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium
Synonyma:
Macusine A;(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium
CBNumber:
CB32256172
Summenformel:
C22H2703N;
Molgewicht:
0
MOL-Datei:
Mol file

(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium Eigenschaften

Schmelzpunkt:
252°
alpha 
D25 -57.5° (c = 1.45)

Sicherheit

(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The bark of Strychnos toxifera yields three closely-related quaternary alkaloids, Macusines A, Band C. This particular base has been isolated as the crystalline chloride which forms clusters of prisms from EhOH-Et20, m.p. 252°C after sintering at 248°C; [α]25D - 57.5° (c 1.455, H20). The alkaloid also forms the iodide, best crystallized from aqueous MeOH, m.p. 274°C (dec.) and the picrate, m.p. 255°C (dec.). The l6-epimer of this base is Macusine C.

Einzelnachweise

Battersby et al., 1. Chern. Soc., 1848 (1960) McPhail et al., Proc. Chern. Soc., 223 (1961) McPhail, Robertson, Sim.,J. Chern. Soc., 1832 (1963) Battersby, Yeowell., ibid, 4419 (1964)

(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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  • (16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium
  • Macusine A
  • 6801-39-4
  • C22H2703N
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