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Sevelamer carbonate

Sevelamer carbonate Struktur
845273-93-0
CAS-Nr.
845273-93-0
Englisch Name:
Sevelamer carbonate
Synonyma:
Sevelam;Sevelam carbonate;Sevelamer carbonate;SEVELEMER CARBONATE;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
CBNumber:
CB32128754
Summenformel:
C7H14ClNO4
Molgewicht:
211.64
MOL-Datei:
845273-93-0.mol

Sevelamer carbonate Eigenschaften

storage temp. 
Room Temperature, under inert atmosphere
L?slichkeit
<4.74mg/mL in DMSO
Aggregatzustand
Solid
Farbe
White to Pale Beige
InChI
InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4)
InChIKey
PADGNZFOVSZIKZ-UHFFFAOYSA-N
SMILES
C(O)(O)=O.C(C1OC1)Cl.C(=C)CN
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS)
Alarmwort
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Sevelamer carbonate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.

Verwenden

Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.

Mode of action

The active substance in Sevelamer carbonate Winthrop, sevelamer carbonate, is a phosphate binder. When taken with meals, it attaches in the gut to phosphate from the food, thereby preventing the phosphate from being absorbed into the body and helping to reduce phosphate levels in the blood.

Sevelamer carbonate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sevelamer carbonate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 206)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Protheragen-ING
+16313385890
info@protheragen-ing.com United States 3868 58
airuikechemical co., ltd.
+undefined86-15315557071
sales02@sdzhonghuimaterial.com China 983 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902
angelia@hbmojin.com China 1176 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Jinan Jianfeng Chemical Co., Ltd
0531-88110457; +8615562555968
info@pharmachemm.com China 251 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 742 58

845273-93-0()Verwandte Suche:


  • 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
  • Sevelamer carbonate
  • Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine
  • Sevelam
  • 2-Propen-1-amine polymer with (chloromethyl)oxiran
  • 2-Propen-1-aminepolymerwith
  • carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine
  • SIM862 Sevelamer Carbonate-----25gm
  • Sevelamer Carbonate, Technical Grade
  • 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate ISO 9001:2015 REACH
  • Sevelam carbonate
  • SEVELEMER CARBONATE
  • 845273-93-0
  • C3H7NmC3H5ClOnCH2O3x
  • C3H7NC3H5ClOxxCH2O3
  • Inhibitors
  • Pharmaceutical intermediate
  • Other APIs
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