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pyridoxal isonicotinoyl hydrazone

pyridoxal isonicotinoyl hydrazone Struktur
737-86-0
CAS-Nr.
737-86-0
Englisch Name:
pyridoxal isonicotinoyl hydrazone
Synonyma:
NSC 77674;PIH - CAS 737-86-0 - Calbiochem;Pyridoxal isonicotinoyl hydrazine;PIH(Pyridoxal isonicotinoyl hydrazine);Pyridoxal isonicotinoyl hydrazone (PIH);inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
CBNumber:
CB31370372
Summenformel:
C14H14N4O3
Molgewicht:
286.29
MOL-Datei:
737-86-0.mol

pyridoxal isonicotinoyl hydrazone Eigenschaften

Schmelzpunkt:
261-262 °C (decomp)
Dichte
1.35±0.1 g/cm3(Predicted)
storage temp. 
+2C to +8C
L?slichkeit
DMF: 1 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.5 mg/ml
Aggregatzustand
Yellow solid
pka
8.04±0.10(Predicted)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

pyridoxal isonicotinoyl hydrazone Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Pyridoxal Isonicotinoyl Hydrazone is a cell-permeable non-toxic iron chelator of the aroyl hydrazone class.

Allgemeine Beschreibung

A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No. 252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity.

pyridoxal isonicotinoyl hydrazone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


pyridoxal isonicotinoyl hydrazone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 42)Lieferanten
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ATK CHEMICAL COMPANY LIMITED
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.

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Aladdin Scientific
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  • Pyridoxal isonicotinoyl hydrazone (PIH)
  • NSC 77674
  • PIH(Pyridoxal isonicotinoyl hydrazine)
  • PIH - CAS 737-86-0 - Calbiochem
  • Pyridoxal isonicotinoyl hydrazine
  • 4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
  • N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
  • inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor
  • N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
  • 737-86-0
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