4-[(2,2-Dimethylpropionyl)amino]buttersure
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- CAS-Nr.
- 69542-93-4
- Bezeichnung:
- 4-[(2,2-Dimethylpropionyl)amino]buttersure
- Englisch Name:
- Pivagabine
- Synonyma:
- Tonerg;CXB 722;Pivagabine;PG 2 (pharmaceutical);4-PivalaMidobutanoic acid;4-(Pivaloylamino)butanoic acid;N-trimethylacetyl-4-aminobutyric acid;4-(2,2-Dimethylpropionamido)butanoic acid;4-[(2,2-dimethylpropionyl)amino]butyric acid;Butanoic acid,4-[(2,2-diMethyl-1-oxopropyl)aMino]-
- CBNumber:
- CB2928582
- Summenformel:
- C9H17NO3
- Molgewicht:
- 187.24
- MOL-Datei:
- 69542-93-4.mol
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4-[(2,2-Dimethylpropionyl)amino]buttersure Eigenschaften
- Siedepunkt:
- 397.0±25.0 °C(Predicted)
- Dichte
- 1.053±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Soluble in DMSO
- pka
- 4.66±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-[(2,2-Dimethylpropionyl)amino]buttersure Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Tonerg was launched in Italy for treatment of acute and post traumatic stress
syndrome and "burnout" syndrome. It inhibits hypothalamic release of corticotropinreleasing
factor (CRF) and effectively antagonizes the activation of CRF induced
stress (neuroendocrine, autonomic and behavior responses). Tonerg is an atypical
antidepressant because it does not involve the monoaminergic system and differs in
effect from benzodiazepines (complete opposite effect of Diazepam). The entire
molecule is responsible for activity. It is lipophilic, orally bioavailable, and has a halflife
of 4-6 hr. Tonerg has a positive effect on sleep disorders by reducing insomnia,
improving anxiety by 20% and depression by 23%.
Originator
Angelini (Italy)
Trademarks
Tonerg
4-[(2,2-Dimethylpropionyl)amino]buttersure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-[(2,2-Dimethylpropionyl)amino]buttersure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 35)Lieferanten
- 4-[(2,2-dimethylpropionyl)amino]butyric acid
- 4-(Pivaloylamino)butanoic acid
- 4-PivalaMidobutanoic acid
- CXB 722
- PG 2 (pharmaceutical)
- Tonerg
- Butanoic acid,4-[(2,2-diMethyl-1-oxopropyl)aMino]-
- Pivagabine
- N-trimethylacetyl-4-aminobutyric acid
- 4-(2,2-Dimethylpropionamido)butanoic acid
- Pivagabine,blood-brain,γ-Aminobutyric acid Receptor,psychoactive,CXB722,derivative,Inhibitor,inhibit,foot,factor,barrier,CXB 722,shock,Gamma-aminobutyric acid Receptor,GABA Receptor,neuromodulatory,corticotropin-releasing
- 69542-93-4
