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2-Thiothymidine

2-Thiothymidine Struktur
28585-51-5
CAS-Nr.
28585-51-5
Englisch Name:
2-Thiothymidine
Synonyma:
2-THIOTHYMIDINE;Thymidine, 2-thio-;2-Thio-2'-deoxythymidine;2'-deoxy-5-methyl-2-thiouridine;1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
CBNumber:
CB2693213
Summenformel:
C10H14N2O4S
Molgewicht:
258.29
MOL-Datei:
28585-51-5.mol

2-Thiothymidine Eigenschaften

Aggregatzustand
Solid
Farbe
White to off-white
InChI
InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKey
PISWNSOQFZRVJK-XLPZGREQSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O

Sicherheit

2-Thiothymidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

2-Thiothymidine is a mRNA therapy used for treatment of ornithine transcarbamylase deficiency.

Application

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

2-Thiothymidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-Thiothymidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
0371-55159968 18137130222
 haifeng.zhang@pannacean.com China 645 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894
 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739
 info@dycnchem.com China 52849 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629
 sales@newcanbio.com China 9981 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58
Hunan Jibang Biological Technology Co., LTD 		+8613776644403
 sales02@kingboomtech.com China 1804 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58

28585-51-5()Verwandte Suche:

  • 2-THIOTHYMIDINE
  • 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
  • 2-Thio-2'-deoxythymidine
  • 2'-deoxy-5-methyl-2-thiouridine
  • 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
  • Thymidine, 2-thio-
  • 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
  • 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
  • 28585-51-5
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