C6 D-threo Ceramide (d18:1/6:0) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
C6 D-
threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-
threo Ceramide is cytotoxic to U937 cells
in vitro (IC
50 = 18 μM). It is metabolically inactive and, unlike C6 L-
erythro ceramide , C6 D-
threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-
threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate (PMA; ) in EL4 T cells when used at a concentration of 10 μM. [Matreya, LLC. Catalog No. 1809]
C6 D-threo Ceramide (d18:1/6:0) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte