3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure
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- CAS-Nr.
- 29915-38-6
- Bezeichnung:
- 3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure
- Englisch Name:
- TAPS
- Synonyma:
- TAP;3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;TAPS;TAPS,99%;TAPS,min;TAPS BIOXTRA;TAPS, ULTROL;Taps, puriss;TAPS ULTRAPURE;TAPS SIGMAULTRA
- CBNumber:
- CB2433242
- Summenformel:
- C7H17NO6S
- Molgewicht:
- 243.28
- MOL-Datei:
- 29915-38-6.mol
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3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure Eigenschaften
- Schmelzpunkt:
- 230-235 °C (dec.)
- Dichte
- 1.4290 (rough estimate)
- Brechungsindex
- 1.6370 (estimate)
- Flammpunkt:
- 110 °C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- H2O: 1 M at 20 °C, clear, colorless
- pka
- 8.55; pKa (37°): 8.1; pKa2 (25°): 8.28
- Aggregatzustand
- Solid
- Farbe
- White
- Geruch (Odor)
- Odorless
- S?ure-Base-Indikators(pH-Indikatoren)
- 7.7 - 9.1
- Wasserl?slichkeit
- Soluble
- Merck
- 13,9148
- BRN
- 2452420
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents
- InChIKey
- YNLCVAQJIKOXER-UHFFFAOYSA-N
- CAS Datenbank
- 29915-38-6(CAS DataBase Reference)
- EPA chemische Informationen
- 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (29915-38-6)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher |
Xi |
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R-S?tze: |
36/37/38 |
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S-S?tze: |
22-24/25-36-26 |
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WGK Germany |
3 |
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TSCA |
Yes |
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HazardClass |
IRRITANT |
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HS Code |
29221980 |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
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Sicherheit |
P261 |
Einatmen von Staub vermeiden. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
TAPS is a zwitterionic buffering agent used in biochemistry and molecular biology. It is part of the Tris family of buffers and is useful for a pH range of 7.7 – 9.1. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers[1]. The solubilities of TAPS in aqueous solution decrease with increasing concentration of the salts (salting-out effect)[2]. TAPS is the preferred culture media buffer used for dinoflagellate experiments, allowing for minimal pH change and maximal growth. It is also often used in capillary electrophoresis to analyze DNA and in planar chromatography to separate dyes. TAPS may form a complex with some common metals so stability constants and concentrations should be taken into account when choosing this buffer. TAPS is capable of inhibiting connexin channels in animal cells.
Chemische Eigenschaften
White/clear crystalline powder
Verwenden
A zwitterionic Good's Buffer
Application
TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.
3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 407)Lieferanten
29915-38-6(3-(Tris(hydroxymethyl)methylamino)propan-1-sulfonsure)Verwandte Suche:
- 3-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]PROPANESULFONIC ACID
- 3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]-PROPANESULPHONIC ACID
- 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid
- [2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)-1-PROPANESULFONIC ACID
- TAPS
- N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANESULFONIC ACID
- N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANE-SULPHONIC ACID
- TAPS, for biochemistry, 99+%
- TAPS,BIOLOGICALBUFFER
- TRIS-PROPANESULFONICACID
- N-[Tris(hydroxymethyl)methyl]-3-amino propanesulfonic acid (TAPS)
- 3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID TAPS
- TAPS ULTRAPURE
- N-[tris(hydroxymethyl)methyl]-3-amionpropanesulfonicacid
- N-TRIS(HYDROXYMETHYL) METHYL-3-AMINOPROPANE SULPHONIC ACID extrapure
- N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid
- 3-(tris(Hydroxymethyl)methylamino)propane-1-sulfonic acid
- 3-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
- Taps, 99+%, for biochemistry
- TAPS, for biochemistry
- 3-[2-Hydroxy-1,1-bis(hydroxymethyl)ethylamino]propane-1-sulfonic acid
- N-(3-Sulfopropyl)tris(hydroxymethyl)methaneamine
- 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic acid >99%
- N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component for biological research]
- TAPS,99%
- N-Tris(Hydroxymethy)methyl-3-aminopropanesulfonic acid
- 3-[Tris(hydroxymethyl)methylamino]-1-propan
- N-(tris(hydroxymethy
- N-Tris (hydroxyMethy) Methyl-3-aMinopropanesulfonic acid(TAPS)
- Tris(hydroxymethyl)methyl-3-aminopropane sulfonic acid
- 1-Propanesulfonic acid, 3-2-hydroxy-1,1-bis(hydroxymethyl)ethylamino-
- 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonicaci
- tris(hydroxymethyl)methylaminopropansulfonic
- tris(hydroxymethyl)methylaminopropansulfonicacid
- tris-Hydroxymethyl methylamino-3-propane sulfonic acid
- TAPS FREE ACID, BIOTECHNOLOGY PERFORMANC E CERTIFIED
- N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINO-PR OPANESULFONIC ACI
- TAPS SIGMAULTRA
- TAPS, MINIMUM 99.5% (TITRATION)
- TAPS FREE ACID CRYSTALLINE
- Taps3-[Tris(Hydroxymethyl)Methylamino]-1-PropanesulfonicAcid
- Taps(N-Tris[Hydroxymethyl]Methyl-3-AminoPropanesulfonicAcid)
- 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic acid (TAPS)
- TAPS (N-Tris[hydroxyMethyl]Methyl-3-aMinopropanesulfonic acid),Free Acid
- 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic (TAPS)
- 3-(tris(hydroxymethyl)methylamino)propane-1-sulphonic acid
- Vesicle-docking protein
- N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid
- TAPS Vetec(TM) reagent grade, 99.5%
- N-[Tris(hydroxymethyl)metyl]-3-aminopropanesulfonic acid
- 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic
- N-[Tris(hydroxymethyl)methyl]-3-aminopranesulfonic acid
- TAPS BIOXTRA
- TAPS, BIOPERFORMANCE CERTIFIED, CELL
- TAPS, ULTROL
- TAPS, ULTROL Grade - CAS 29915-38-6 - Calbiochem
- Tris(hydroxymethyl)methylaminopropanesulfonic acid
- 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]ammonio]-1-propanesulfonate