Phthalylsulfathiazol
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Phthalylsulfathiazol Eigenschaften
- Schmelzpunkt:
- 198-204°C
- Siedepunkt:
- 371.31℃[at 101 325 Pa]
- Dichte
- 1.4235 (rough estimate)
- Dampfdruck
- 0Pa at 25℃
- Brechungsindex
- 1.6390 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in ethanol (96 per cent).
- Aggregatzustand
- Solid
- pka
- 3.40±0.36(Predicted)
- Farbe
- White to Light Yellow
- Wasserl?slichkeit
- 400mg/L at 28℃
- Merck
- 14,7377
- BRN
- 359901
- LogP
- -2 at 28℃
- CAS Datenbank
- 85-73-4(CAS DataBase Reference)
- NIST chemische Informationen
- Phthalylsulfathiazole(85-73-4)
- EPA chemische Informationen
- Benzoic acid, 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]- (85-73-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
S-S?tze: | 24/25 | ||
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RIDADR | 3249 | ||
RTECS-Nr. | TH8575000 | ||
HazardClass | 6.1(b) | ||
PackingGroup | III | ||
HS Code | 29350090 | ||
Toxizit?t | LD50 i.p. in mice: 920 mg/kg (Mattis) |
Bildanzeige (GHS) | |||||||||||||||
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Alarmwort | Achtung | ||||||||||||||
Gefahrenhinweise |
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Sicherheit |
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Phthalylsulfathiazol Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White or yellowish-white, crystalline powder.Verwenden
Phthalylsulfathiazole is a sulfonamide antibacterial drug with similar and stronger effects than Sulfaguanidine and Succinylsulfathiazole. It is rarely absorbed orally and slowly decomposes in the intestine to release Sulfathiazole and exert intestinal antibacterial effects, and is used in the treatment of dysentery, colitis, and gastroenteritis.Definition
ChEBI: Phthalylsulfathiazole is a sulfonamide incorporating 2-carboxybenzamido and 1,3-thiazol-2-yl moieties that is a broad-spectrum antibiotic indicated in the treatment of dysentery, colitis, gastroenteritis and intestinal surgery. It is a sulfonamide, a member of 1,3-thiazoles, a dicarboxylic acid monoamide and a sulfonamide antibiotic. It derives from a phthalic acid.synthetische
It may be prepared by the interaction of sulfathiazole and phthalic anhydride in equimolar proportions.It exerts its bacteriostatic effect in the gastro-intestinal tract. It has been found to be twice as active as sulfaguanidine in the treatment of bowel irregularities. It is often effective in watery diarrhoeas and ulcerative colitis. It is also used in the pre-operative treatment of patients undergoing surgery of the intestinal tract. It may also be recommended in the treatment of acute bascillary dysentry of the Sonne, Flexner and Shiga species.
Weltgesundheitsorganisation (WHO)
Phthalylsulfathiazole, a sulfonamide anti-infective agent, was introduced in 1946 for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. Although phthalylsulfathiazole, which is poorly absorbed from the gastrointestinal tract, is no longer recommended in some countries, it continues to be used in others for the treatment of local intestinal infections, including bacterial dysentery, and for pre-operative bowel preparation.Phthalylsulfathiazol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Phthalylsulfathiazol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 259)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8816 | 58 |
Hebei ZB Gamay Biological Technology Co.,Ltd | +8617330018573 |
info@zbvet.net | China | 245 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21639 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 |
info@tnjchem.com | China | 2986 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29886 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 |
sales@amoychem.com | China | 6383 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 |
info@longyupharma.com | China | 2524 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
85-73-4(Phthalylsulfathiazol)Verwandte Suche:
1,3-Diphenylpropan-1,3-dion
2-Aminothiazol
Pyrazophos (ISO)
Sulfathiazolnatrium
ALTRENOGEST
Sulfanilamid
Phenylvalerat
Sulfathiazol
Glycin
4-Aminobenzoesure
Thiazol
Dibenzoylperoxid
Phenylhydrazin
N-(4-(Acetylsulfamoyl)phenyl)phthalamidsure
2,3-Dihydrophthalazin-1,4-dion
2,3-Benzodiazin
Phthalsureanhydrid
Anthranilic acid
- 4'-(2-THIAZOLYLSULFAMYL)PHTHALANILIC ACID
- 2-[[[4-[(2-THIAZOLYLAMINO)SULFONYL]PHENYLAMINO]CARBONYL]BENZOIC ACID
- 2-(N4-PHTHALYSULFANILAMIDO)THIAZOLE
- 2-(N-PHTHALYLAMINOBENZENESULFONAMIDO)THIAZOLE
- N4-PHTHALYLSULFATHIAZOLE
- PST
- PHTHALYLSULFATHIAZOLE
- PHTHALYLSULFATHIOZOLE
- PHTHALYLSULPHATHIAZOLE
- SULFATHALIDINE
- 4-(2-THIAZOLYLSULFAMYL)PHTHALANILIC ACID 95+%
- 2-[(((4-[(2-Thiozolylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid
- 2-[[4-[(2-Thiazolyl)sulfamoyl]phenyl]carbamoyl]benzoic acid
- N-[4-(2-Thiazolylsulfamoyl)phenyl]phthalamic acid
- N-[4-(2-Thiazolylsulfamoyl)phenyl]phthalamidic acid
- Phthalylsulfathiazo
- Phtalylsulfathiazole
- (o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole
- 2-((4-[(1,3-Thiazol-2-ylamino)sulfonyl]anilino)carbonyl)benzoic acid
- 2-(n(sup4)-phthalyaminobenzenesulfonamide)thiazole
- 2-(n(sup4)-phthalyaminobenzenesulfonamido)thiazole
- 2-(n(sup4)-phthalylsulfanilamido)thiazole
- 2-(N4-phthalyaminobenzenesulfonamide)thiazole
- 2-(N4-phthalyaminobenzenesulfonamido)thiazole
- 2-(N4-phthalylsulfanilamido)thiazole
- 2-(N4-Phthalylaminobenzenesulfonamide)thiazole
- 2-(p-N-Phthalylsulfanilyl)aminothiazole
- 2-(p-Phthalylaminobenzenesulfamido)thiazole
- 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-benzoicaci
- 4'-(2-Thiazolylsulfamoyl)phthalanilic acid
- Talidine
- Taloudron
- Thalazole
- Thalinil
- Thalistanin
- Thalistatyl
- Ultratiazol
- Anti-ST8SIA4 antibody produced in rabbit
- MGC34450
- MGC61459
- ST8SIA4
- Anti-MGC34450
- Anti-MGC61459
- Anti-PST
- Anti-PST1
- Anti-ST8 α-N-acetyl-neuraminide α-2,8-sialyltransferase 4
- Anti-HAST1/HAST2
- Anti-MGC5163
- Anti-ST1A3
- Anti-STP1
- Anti-sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
- N4-PHTHALYLSULFATHIAZOLE VETRANAL, 250
- PHTHALYLSULFATHIAZOLE(PST)
- PhthalylsulphathiazolePhthalylsulphathiazoleBp
- 2-((4-(N-(Thiazol-2-yl)sulfaMoyl)phenyl)carbaMoyl)benzoic acid
- Phthalyslsulfathiazole(PST)
- N4-Phthalylsul
- 4’-(2-thiazolylsulfamoyl)-phthalanilicaci