Elastase
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- CAS-Nr.
- 9004-06-2
- Bezeichnung:
- Elastase
- Englisch Name:
- Elastase
- Synonyma:
- ELA2;ELANE;elaszym;ELASTASE;Eiastase;Elastase-2;e.c.3.4.4.7;Elastase ES;EC 3.4.21.37;EC 3.4.21.36
- CBNumber:
- CB2398822
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Elastase Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- lyophilized powder
- Farbe
- White to off-white
- CAS Datenbank
- 9004-06-2
- EPA chemische Informationen
- Elastase (9004-06-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
B |
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| WGK Germany |
3 |
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| F |
3-10 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Elastase Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Elastase from human leukocytes has been used:
- to measure serum elastase activity
- in proteolytic digestion of fibronectin and salivary glands
- in neutrophil elastase (NE) activity assay
- cell-free NE digestion of E-cadherin
- scratch wound assay
- in a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal models
Elastase has been used to digest fibronectin. The results were compared with fibronectin digestion by crude human leukocyte homogenate to examine the presence of fibronectin peptides in saliva of patients with Sj?gren′s syndrome. It has also been used as a reference to determine the elastase activity in cell lysates. This study examined the effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells. These blast cells were from patients with acute promyelocytic leukemia.
Allgemeine Beschreibung
Elastase is a proteolytic enzyme. It is a member of the subgroup named, peptidyl peptide hydrolases. It is a major anatomic constituent of arteries. It is mainly found in the pancreas and pancreatic juice of various birds and mammals. It is also present in human serum, granulocytes and erythrocytes.
Biochem/physiol Actions
Elastase enzyme is capable of releasing soluble peptides from insoluble elastin fibers with the help of a proteolytic process. It can stimulate disintegration of the axoneme with the help of adenosine triphosphate (ATP). Unlike pancreatic elastase the leukocyte enzyme has a preferential cleavage for the carboxyl side of valine, but will also cleave to a lesser extent after alanine. Natural substrates include elastin, cartilage proteoglycans, collagen types I, II, II and IV, and fibronectin.
Elastase Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Elastase Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 70)Lieferanten
9004-06-2(Elastase)Verwandte Suche:
- PANCREATOPEPTIDASE E
- LYSOSOMAL ELASTASE
- macrophage metalloelastase
- EC 3.4.21.36
- EC 3.4.21.37
- ELASTASE
- ELASTASE, LEUKOCYTE
- ELASTASE, NEUTROPHIL, HUMAN
- ELASTASE, HUMAN NEUTROPHIL
- ELASTASE, HUMAN NEUTROPHILS
- elaszym
- LEUKOCYTE ELASTASE, HUMAN NEUTROPHILS
- e.c.3.4.4.7
- elastolytic enzyme
- pancre-atopeptidase
- elastase from human leukocytes
- Eiastase
- ELASTASE, LEUKOCYTE FROM HUMAN*LEUKOCYTE S
- ELASTASE 2X-CRYSTALLIZED
- ELASTASE FROM PORCINE PANCREAS LYOPHILIZED POWDER
- ELASTASE FROM HUMAN NEUTROPHILS (WHITE LEUCOCYTES)ACTIVITY: 18-30 UNITS/MG PROTEIN SALT-FREE, LYOPHILIZED SOLID 98% BY SDS-PAGE
- Elastase ES
- 3-(4-hydroxy-2,3-dimethoxy-phenyl)-3,4-dihydro-2H-chromen-7-ol
- 3-(4-hydroxy-2,3-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-ol
- 3-(4-hydroxy-2,3-dimethoxy-phenyl)chroman-7-ol
- Elastase from human neutrophils min. 10 U/mg
- ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit
- Bone marrow serine protease
- ELA2
- ELANE
- Elastase-2
- Elastasefromhumanneutrophils(whiteleucocytes),activity:18-30u/mgproteinsalt-free,lyophilizedsolid
- fromporcinepancreaslyophilizedpowder
- Elastase from porcine pancreas, lyophil.
- Elastase froM huMan neutrophils Min. 10 U/Mg lyophil.
- neutrophil elastase
- Elastase， human leucocytes
- 9004-06-2
- 9004-02-6
- 9004-6-2
- Enzymes, Inhibitors, and Substrates
- BioChemical
- Biochemicals and Reagents
- Proteolytic Enzymes and Substrates
- Proteolytic Enzymes
