OREXIN B (HUMAN) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC₅₀ values of 420 and 36 nM for human recombinant OX₁ and OX₂ receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX₁ and OX₂ (EC₅₀s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX₁ (EC₅₀ = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.

Biochem/physiol Actions

Orexins/Hypocretins, Orexin A/ hypocretin-1 and Orexin B/ hypocretin-2, are excitatory neuropeptides that mediate there effects via two receptors, OX-1 and OX-2. Orexins are involved in food intake, obesity regulation, energy homeostasis and differentiation.

OREXIN B (HUMAN) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

OREXIN B (HUMAN) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10311	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22784	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58

205640-91-1()Verwandte Suche:

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• REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
• Orexin B (huMan) Hypocretin-2 (huMan)
• OREXIN B HUMAN ≥98%
• ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
• HYPOCRETIN-2
• HYPOCRETIN-2, HUMAN
• H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
• RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
• OREXINS OREXIN B HUMAN
• OREXIN B (HUMAN)
• Orexin B (human), ≥98% (HPLC)
• PubChem ID: 90479794
• Orexin B (human) (trifluoroacetate salt)
• Human orexin B
• L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
• OREXIN B (HUMAN) USP/EP/BP
• Orexin B（Human）（Leu* U-13C6,15N）
• 205640-91-1
• C123H212N44O35S
• C123H212N44O35S1
• proteins
• Peptide
• Orexin receptor