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Piracetam

Piracetam Struktur
7491-74-9
CAS-Nr.
7491-74-9
Bezeichnung:
Piracetam
Englisch Name:
Piracetam
Synonyma:
Nootropil;Pyracetam;2-(2-OXOPYRROLIDIN-1-YL)ACETAMIDE;Geram;CI-871;Axonyl;Cl-781;kt-801;Piramem;Euvifor
CBNumber:
CB2354473
Summenformel:
C6H10N2O2
Molgewicht:
142.16
MOL-Datei:
7491-74-9.mol

Piracetam Eigenschaften

Schmelzpunkt:
151-152,5 C
Siedepunkt:
259.72°C (rough estimate)
Dichte
1.2298 (rough estimate)
Brechungsindex
1.5010 (estimate)
storage temp. 
2-8°C
L?slichkeit
Freely soluble in water, soluble in ethanol (96 per cent). It shows polymorphism (5.9).
Aggregatzustand
Solid
pka
15.67±0.40(Predicted)
Farbe
Crystals from isopropanol
Wasserl?slichkeit
Soluble in water (100mM)
InChI
InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)
InChIKey
GMZVRMREEHBGGF-UHFFFAOYSA-N
SMILES
N1(CC(N)=O)CCCC1=O
CAS Datenbank
7491-74-9(CAS DataBase Reference)
NIST chemische Informationen
Piracetam(7491-74-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-37/39-24/25
WGK Germany  2
RTECS-Nr. UX9660500
HS Code  29339900
Giftige Stoffe Daten 7491-74-9(Hazardous Substances Data)
Toxizit?t LD50 oral in mouse: 2gm/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Piracetam Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Piracetam is a nootropic agent with an indication as adjunctive treatment for myoclonus of cortical origin, as well as tardive dyskinesia. However, piracetam is not approved by the FDA for any medical use in the USA. Piracetam should not be prescribed in patients with Huntington disease, those with serious kidney problems, or patients who have experienced a brain haemorrhage. Bleeding problems are a further caution to be taken into account. Although there is little evidence for piracetam’s efficacy in terms of long- term benefits for the treatment of mild cognitive impairments, recent studies showed that it is effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins. With regard to piracetam’s behavioural profile, its beneficial effects on lowering depression and anxiety appear to be higher than its positive effects on memory.

Chemische Eigenschaften

White crystalline powder. Odorless, slightly bitter taste. Soluble in water, slightly soluble in ethanol, almost insoluble in ether.

Verwenden

Piracetam has been used to study crystal structure and physicochemical properties of six co-crystals of piracetam. It has also been used to study its in vitro antioxidant properties.

Verwenden

Piracetam is most commonly used for breath-holding attacks, seizure disorder (epilepsy), antinauseant, dizziness (vertigo), a learning disorder marked by difficulty reading (dyslexia), nootropic, cortical myoclonus, and a movement disorder often caused by antipsychotic drugs (tardive dyskinesia).

synthetische

Prepared by condensing 2-pyrrolidinone with ethyl chloroacetate in the presence of a metal hydride and then converting the ester into an amide with ammonia.

Definition

ChEBI: Piracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. It is a compound suggested to be both a nootropic and a neuroprotective agent.

Biologische Aktivit?t

Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux; potentiates Na + influx through AMPA receptors. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.

Sicherheitsprofil

Mildly toxic by ingestion. Whenheated to decomposition it emits toxic fumes of NOx.

Stoffwechsel

The plasma half life of piracetam is approximately 5 hours following oral or intravenous administration. The half life in the cerebrospinal fluid was 8.5 hours. The apparent total body clearance is 80-90 mL/min.

l?uterung methode

This typical nootropic (Alzheimer) drug modulates Na flux in AMPA receptors and is purified by recrystallisation from isoPrOH. [Gouilaev & Senning Brain Research Rev 19 180 1994.]

Piracetam Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Piracetam Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 517)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Nutra Biotechnology Co.,Ltd
+8617786394783
nutrabiotech@outlook.com China 300 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58
APOLLO HEALTHCARE RESOURCES
+6596580999
sales@apollo-healthcare.com.sg Singapore 399 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097
market02@senwayer.com China 904 58
Wuhan Quanjinci New Material Co.,Ltd.
+86-15271838296; +8615271838296
kyra@quanjinci.com China 1512 58
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902
angelia@hbmojin.com China 1176 58
Shaanxi Xianhe Biotech Co., Ltd
+8617709210191
Jerry@xhobio.com China 882 58
Guangdong Junhua Chemical Co., Ltd
+86-075785239927 +86-13326778444
aron@hjococ.com China 35 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58

7491-74-9(Piracetam)Verwandte Suche:


  • IFLAB-BB F1918-0022
  • 2-(2-OXOPYRROLIDINO)ACETAMIDE
  • 2-OXO-1-PYRROLIDINEACETAMIDE
  • N-CARBAMOYLMETHYL-2-PYRROLIDINONE
  • 2-Oxo-1-pyrrolidinacetamide
  • Piracetam, Vetranal
  • PiracetamEp2002DmfGmp
  • 1-Acetamido-2-pyrrolidinone
  • 1-Pyrrolidineacetamide, 2-oxo-
  • 1-Pyrrolidineacetamide,2-oxo-
  • 2-(2-Oxo-1-pyrrolidinyl)acetamide
  • 2-Ketopyrrolidine-1-ylacetamide
  • 2-oxo-1-pyrrolidineacetamid
  • 2-Oxo-pyrrolidin-1-ylacetamide
  • 2-Oxo-pyrrolidine acetamide
  • 2-oxo-pyrrolidineacetamide
  • 2-Pyrrolidinoneacetamide
  • 2-Pyrrolidoneacetamide
  • 2-(2-Oxopyrrolidino)acetamide, 2-Oxo-1-pyrrolidineacetamide
  • CI-871
  • Piramem
  • 2-(2-ketopyrrolidin-1-yl)acetamide
  • 2-(2-oxopyrrolidin-1-yl)ethanamide
  • (2-Oxopyrrolidino)acetaMide
  • OxiracetaM IMp.I
  • PIRACETAM
  • Avigilen
  • Axonyl
  • Cerebroforte
  • ciclofalina
  • Cl-781
  • Encetrop
  • Euvifor
  • Gabacet
  • Genogris
  • Geram
  • kt-801
  • naofukang
  • Nootron
  • Nootrop
  • Nootropyl
  • Normabrain
  • Norzetam
  • Pirazetam
  • Pirroxil
  • Pyramem
  • UCB 6215
  • ucb6215
  • PiracetaM, EP
  • Piracetam, >=99%
  • 2-oxopyrrolidin-l-ylacetamide
  • oxiracetam impurity V
  • Oxiracetam-5
  • Piracetam(Naofukang)
  • Oxiracetam impurity G
  • Laci Staw
  • Piracetam Cas number:7491-74-9
  • Piracetam/Nootropyl
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