6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on
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- CAS-Nr.
- 51649-83-3
- Bezeichnung:
- 6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on
- Englisch Name:
- 6-Aminofluorescein
- Synonyma:
- 6-AF;6-AFM;(isoMer II);6-AMINOFLUORESCEIN;6-AMinofluorescein 6-Aminofluorescein (6-AF);AMINOFLUORESCEIN ISOMER II;FLUORESCEINAMINE, ISOMER 2;FLUORESCEINMINE, ISOMER 2,;FLUORESCEINAMINE, ISOMER II
- CBNumber:
- CB2300526
- Summenformel:
- C20H13NO5
- Molgewicht:
- 347.32
- MOL-Datei:
- 51649-83-3.mol
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6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on Eigenschaften
- Schmelzpunkt:
- 285 °C (dec.)(lit.)
- Siedepunkt:
- 481.89°C (rough estimate)
- Dichte
- 1.3724 (rough estimate)
- Brechungsindex
- 1.5180 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- methanol: soluble1mg/mL, clear, yellow to very dark yellow-orange
- pka
- 9.34±0.20(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Yellow to Orange
- BRN
- 51708
- Stabilit?t:
- Light and Moisture Sensitive
- InChI
- InChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
- InChIKey
- YOAWSYSKQHLFPM-UHFFFAOYSA-N
- SMILES
- C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(N)=C1)C(=O)O2
- CAS Datenbank
- 51649-83-3(CAS DataBase Reference)
6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
6-Aminofluorescein (6-AF) is a new fluorescence dye with bright colors and high fluorescence intensity. Its chemical structure history contains a nitrogen group and a fluorescent group. The presence of the fluorescent component enables 6-Aminofluorescein to emit a distinct fluorescent signal when excited, making it valuable for fluorescent labeling and imaging. It is widely used in biological science research, chemical analysis and fluorescence microscopy.
Chemische Eigenschaften
Yellow Solid
Verwenden
Fluorescent labeling reagent for proteins. Glycosaminoglycuronans react with 6-aminofluorescein to yield fluorescent derivatives. Used in the fluorescent antibody technique for rapid identification of pathogens.
Biologische Funktion
6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed "buckysomes". 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein. 6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).
Einzelnachweise
[1] BHARATE G Y, QIN H, FANG J. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging[J]. Journal of Personalized Medicine, 2022, 12. DOI:10.3390/jpm12101650.
[2] Müller, Werner EG, and Heinz Christoph Schr?der, eds. Biological Response Modifiers—Interferons, Double-Stranded RNA and 2′, 5′-Oligoadenylates. Vol. 14. Springer Science & Business Media, 2012.
6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 174)Lieferanten
51649-83-3(6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on)Verwandte Suche:
- 6-amino-3',6'-dihydroxyspiro[isobenzofuran-1(3h),9'-[9h]xanthene]-3-one
- AMINOFLUORESCEIN ISOMER II
- 5-AMINOFLUORESCEIN (ISOMER II)
- FLUORESCEINAMINE, ISOMER 2
- FLUORESCEINAMINE, ISOMER II
- 6-AMINOFLUORESCEIN, FOR FLUORESCENCE
- FLUORESCEINMINE, ISOMER 2,
- 5-AMINOFLUORESCEIN (ISOMER 2)
- 6-Aminofluorescein (isomer II)
- (isoMer II)
- 6-AMinofluorescein
- 6-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one
Fluoresceinamine
- Fluoresceine amine isomer II
- Fluoresceinamine isomer II,97%
- 6-AFM
- 6-AMINOFLUORESCEIN
- 6-AMINO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN]-3-ONE
- 6-Amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
- (4Z)-4-(dimethylaminomethylidene)-5-methyl-2-phenyl-3-pyrazolone
- 6-Aminofluorescein (isomer II)>
- 6-AF
- 6-Aminofluorescein (6-AF)
- Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 6-amino-3',6'-dihydroxy-
- 6’-Amino-3,6-Dihydroxyspiro-3’-One
- 6-Amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
- *Desflurane Impurity 7 (Desflurane EP Impurity G)
- 6-Aminofluorescein, Fluorescent labeling agent
- 51649-83-3
- Fluorescent Labels
- Fluorescent Probes, Labels, Particles and Stains
- Functional Group Reactive Labels for Immunoassays
- Functional Group Reactive Labels
- Carbohydrate Labels for Chromatography
- Carbohydrate Labels
- Biochemicals and Reagents
- BioChemical
- marker
- Fluorescent Labels and Indicators
- Fluorescent Labels & Indicators
