(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
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- CAS-Nr.
- 300543-56-0
- Englisch Name:
- (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
- Synonyma:
- Levocetirizine Impurity A;Levocetirizine Impurity 2;(R)-Cetirizine EP Impurity A;(R)-1-[(4-Chlorophenyl)phenylmethyl;(R)-1-(p-Chlorobenzhydryl)piperazine;Chlorobenzhydryl Piperazine (F02160);(R)-N-(4-Chlorobenzyl hydryl) piperazine;R(-)-1-[(4-Chlorophenyl)benzyl]piperazine;(-)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE;(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine
- CBNumber:
- CB2299774
- Summenformel:
- C17H19ClN2
- Molgewicht:
- 286.8
- MOL-Datei:
- 300543-56-0.mol
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(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Eigenschaften
- Schmelzpunkt:
- 91-93oC
- Siedepunkt:
- 409.1±0.0 °C(Predicted)
- Dichte
- 1.158
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
- pka
- 8.99±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White
- PH
- 9.38 at 25℃ and 10.07g/L
- Wasserl?slichkeit
- Soluble in chloroform, methanol, and dichloromethane. Slightly soluble in water.
- InChI
- InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/t17-/s3
- InChIKey
- UZKBSZSTDQSMDR-SCBJWRGWNA-N
- SMILES
- [C@@H](N1CCNCC1)(C1C=CC=CC=1)C1C=CC(Cl)=CC=1 |&1:0,r|
- CAS Datenbank
- 300543-56-0
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Intermediate in the production of (R)-Cetirizine (C281106).
Application
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine could be used to synthesize a series of novel derivatives. Most of these derivatives significantly affected both allergic asthma and allergic itching. Meanwhile, in the test of allergic itching, five of the 19 compounds have more potent activities than levocetirizine[1].
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 193)Lieferanten
300543-56-0()Verwandte Suche:
- (-)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE
- (R)-(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
- (R)-1-(p-Chlorobenzhydryl)piperazine
- Piperazine,1-[(R)-(4-chlorophenyl)phenylMethyl]-
- (R)-1-[^a-(4-Chlorophenyl)benzyl]piperazine, 97%
- (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine
- Levocetirizine Impurity 2
- Levocetirizine Impurity A
- (130018-88-1) (-)-1-((4-chlorophenyl)phenylmethyl)piperazine
- (R)-Cetirizine EP Impurity A
- (R)-1-[(4-Chlorophenyl)phenylmethyl
- (R)-Cetirizine EP Impurity A (Levocetirizine Impurity 2)
- Levocetirizine Chlorobenzhydryl Piperazine (USP)
- (R)-1-[^a-(4-Chlorophenyl)benzyl]piperazine,97%
- (R)-(-)-1-[(4-chlorophenyl)phenmethyl]piperazine
- (R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine (Cetirizine Impurity)
- Chlorobenzhydryl Piperazine (F02160)
- TIANFUCHEM--(-)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE
- R(-)-1-[(4-Chlorophenyl)benzyl]piperazine
- Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine)
- (-)-1-[( 4-ChIorophenyI)PhenyImethyI] Piperazine
- (R)-N-(4-Chlorobenzyl hydryl) piperazine
- (R)-1-[(4-chlorophenyl)phenyl methyl] Piperazine (Intermediate of Levocetirizine )
- (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
- (R)-Cetirizine EP Impurity A ((R)-Hydroxyzine USP Related Compound A)
- 300543-56-0
- Aromatics
- Chiral Reagents
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Pharmaceutical Intermediates
