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5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Struktur
145915-60-2
CAS-Nr.
145915-60-2
Englisch Name:
5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
Synonyma:
DAPH-7;DAPH 2;CGP 53353;CGP-53353 solid;5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione;PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem;5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE;5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE;1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]-;5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2
CBNumber:
CB2299648
Summenformel:
C20H13F2N3O2
Molgewicht:
365.33
MOL-Datei:
145915-60-2.mol

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Eigenschaften

storage temp. 
2-8°C
L?slichkeit
DMSO: >10mg/mL
Aggregatzustand
solid
Farbe
orange

Sicherheit

WGK Germany  3

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines.

Biologische Aktivit?t

Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro .

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
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  • CGP 53353
  • 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
  • 5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE
  • 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2
  • DAPH 2
  • DAPH-7
  • PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem
  • 1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]-
  • CGP-53353 solid
  • 5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione
  • 145915-60-2
  • C20H13F2N3O2
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Protein Kinase C (PKC)
  • Kinase/Phosphatase Biology
  • Serine/Threonine Kinase Inhibitors
  • Protein Kinase
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