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Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Struktur
179420-17-8
CAS-Nr.
179420-17-8
Englisch Name:
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
Synonyma:
CJ-13610;CJ-13610 (CJ13610);CJ-13610 >=98% (HPLC);Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide;2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-;4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE;Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610
CBNumber:
CB22750572
Summenformel:
C22H23N3O2S
Molgewicht:
393.5
MOL-Datei:
179420-17-8.mol

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Eigenschaften

Schmelzpunkt:
208-210 °C
Siedepunkt:
681.0±65.0 °C(Predicted)
Dichte
1.27±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: ≥10mg/mL
Aggregatzustand
powder
pka
15.77±0.20(Predicted)
Farbe
white to tan

Sicherheit

WGK Germany  3

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling.

Biochem/physiol Actions

CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice.

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 26)Lieferanten
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  • Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
  • CJ-13610
  • CJ-13610 >=98% (HPLC)
  • 2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-
  • CJ-13610 (CJ13610)
  • 4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
  • Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610
  • 179420-17-8
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