N-Octadecyl-N'-propyl-sulfamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARα, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally. N-Octadecyl-N''-propyl-sulfamide is an analog of OEA with selective binding affinity for PPARα. It is a more potent activator of PPARα, exhibiting an EC₅₀ value of 100 nM, compared to OEA, which exhibits an EC₅₀ value of 120 nM. At a dose of 1 mg/kg for 8-11 days, N-octadecyl-N''-propyl-sulfamide induces satiety, thereby decreasing food-intake, body weight, and plasma triglyceride concentration in free-feeding Wistar and obese Zucker (fa/fa) rats.

N-Octadecyl-N'-propyl-sulfamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-Octadecyl-N'-propyl-sulfamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58

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• N-Octadecyl-N'-propyl-sulfamide
• N-(propylsulfamoyl)octadecan-1-amine
• Sulfamide, N-octadecyl-N'-propyl-
• N-Octadecyl-N'-propyl-sulfamide
• 925891-74-3
• C21H46N2O2S