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2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine Struktur
817204-33-4
CAS-Nr.
817204-33-4
Englisch Name:
2'-deoxy-2'-fluoro-2'-C-methylcytidine
Synonyma:
ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130(R 1656);PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine
CBNumber:
CB22525888
Summenformel:
C10H14FN3O4
Molgewicht:
259.23
MOL-Datei:
817204-33-4.mol

2'-deoxy-2'-fluoro-2'-C-methylcytidine Eigenschaften

Schmelzpunkt:
216-218℃
Siedepunkt:
482.4±55.0 °C(Predicted)
Dichte
1.67
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
Methanol (Slightly), Water (Slightly)
pka
12.86±0.70(Predicted)
Aggregatzustand
Solid
Farbe
White to Light Brown
Stabilit?t:
Hygroscopic
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).

Verwenden

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

2'-deoxy-2'-fluoro-2'-C-methylcytidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2'-deoxy-2'-fluoro-2'-C-methylcytidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 135)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
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Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
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CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58

817204-33-4()Verwandte Suche:

  • (2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine
  • PSI-6130;R 1656;PSI 6130
  • 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr
  • 2'-deoxy-2'-fluoro-2'-C-methylcytidine
  • R 1656
  • ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate
  • 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi
  • 4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one
  • R 1656; R-1656; R1656; PSI6130; PSI 6130
  • 2'-deoxy-2'-fluoro-2'-C-methylcytidin
  • 2'-Deoxy-2'-F-2'-C-methylcytidine
  • CS-1995
  • PSI-6130;PSI 6130
  • Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-
  • 2'-deoxy-2'-fluoro-2'-C-methylcytidine,817204-33-4
  • ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate
  • PSI 6130
  • 2'-deoxy-2'-Fluoro-2'-methylcytidine
  • 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (sofosbuvir Impurity)
  • Sofosbuvir Impurity 121
  • 2'-C-methyl-2'-Fluoro-2'-deoxyCytidine
  • 2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • PSI-6130(R 1656)
  • 817204-33-4
  • apis
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