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5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine Struktur
1134156-31-2
CAS-Nr.
1134156-31-2
Englisch Name:
5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
Synonyma:
CS-1647;VER 155088;VER 155008;HSP70 inhibitor;VER-155008, ≥98% (HPLC);VER 155008;VER-155008;VER155008;8-(3,4-Dichlorobenzyl)aMino-5'-O-(4-cyanobenzyl)adenosine;8-(3,4-Dichlorobenzyl)amino-5’-O-(4-cyanobenzyl)adenosine, VER155008;5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine;5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
CBNumber:
CB22518790
Summenformel:
C25H23Cl2N7O4
Molgewicht:
556.4
MOL-Datei:
1134156-31-2.mol

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine Eigenschaften

Siedepunkt:
856.3±75.0 °C(Predicted)
Dichte
1.63±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: >10mg/mL
pka
13.04±0.70(Predicted)
Aggregatzustand
powder
Farbe
white to light brown
InChIKey
ZXGGCBQORXDVTE-UMCMBGNQSA-N

Sicherheit

WGK Germany  3

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

VER 155008 is a novel adenosine-derived inhibitor of heat-shocked protein 70, Hsp70 resulting in an inhibition of cell proliferation of human cancer cell lines.

Biochem/physiol Actions

VER‐155008 positively promotes memory recovery and axonal regrowth. It is also involved in inhibiting cell cycle progression and proliferation in non-small-cell lung cancer (NSCLC).

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 106)Lieferanten
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Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
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TargetMol Chemicals Inc.
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  • VER 155008
  • 4-((((2R,3S,4R,5R)-5-(6-aMino-8-((3,4-dichlorobenzyl)aMino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methoxy)Methyl)benzonitrile
  • 8-(3,4-Dichlorobenzyl)aMino-5'-O-(4-cyanobenzyl)adenosine
  • 4-{(2R,3S,4R,5R)-5-[6-aMino-8-(3,4-dichlorobenzylaMino)purin-9-yl]-3,4-dihydroxytetrahydrofuran-2-ylMethoxyMethyl}benzonitrile
  • VER 155088
  • 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
  • VER-155008, ≥98% (HPLC)
  • 8-(3,4-Dichlorobenzyl)amino-5’-O-(4-cyanobenzyl)adenosine, VER155008
  • Adenosine, 5'-O-[(4-cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-
  • HSP70 inhibitor
  • VER 155008;VER-155008;VER155008
  • CS-1647
  • 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
  • 1134156-31-2
  • C25H23Cl2N7O4
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