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(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester

(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Struktur
2506-26-5
CAS-Nr.
2506-26-5
Englisch Name:
(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester
Synonyma:
Vincamajine;O-Deacetylvincamedine;(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester;Ajmalan-16-carboxylic acid, 19,20-didehydro-17-hydroxy-, methyl ester, (2α,17S,19E)-
CBNumber:
CB22371281
Summenformel:
C22H26N2O3
Molgewicht:
366.46
MOL-Datei:
2506-26-5.mol

(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Eigenschaften

Schmelzpunkt:
226.5-227°C
Siedepunkt:
524.1±50.0 °C(Predicted)
Dichte
1.36±0.1 g/cm3(Predicted)
pka
13.63±0.40(Predicted)

Sicherheit

(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

A minor constituent of Vinca major, this alkaloid has been obtained by chromatography of the alkaloidal fraction followed by recrystallization from MeOH when it forms long, colourless needles. It is laevorotatory with [α]D - 55° (c 0.45, 96% EtOH). The crystalline hydrochloride has m.p. 259-261°C (dec.); [α]D -40° (c 0.38, H2O). One secondary non-phenolic hydroxyl group is present and the O-acetate is identical with Vincamedine (q.v.).

Einzelnachweise

Janot, LeMen., Compt. rend., 241,767 (1955)

(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester
  • Vincamajine
  • Ajmalan-16-carboxylic acid, 19,20-didehydro-17-hydroxy-, methyl ester, (2α,17S,19E)-
  • O-Deacetylvincamedine
  • 2506-26-5
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