AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST
1, SST
2, SST
3, SST
4, and SST
5 (IC
50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST
1, SST
2, SST
3, SST
4, and SST
5 (EC
50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.
AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte