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piperlonguminine

piperlonguminine Struktur
5950-12-9
CAS-Nr.
5950-12-9
Englisch Name:
piperlonguminine
Synonyma:
MEXE;mexedrone;Piperlonguminin;Piperlonguminine;N-Isobutylpiperamide;Mexedrone MEXE MDPHP BK-2CB;Mexedrone Cas no.: 5950-12-9 White crystal 99%;5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide;(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-isobutyl-penta-2,4-dienamide;5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2E,4E-pentadienamide
CBNumber:
CB21562460
Summenformel:
C16H19NO3
Molgewicht:
273.33
MOL-Datei:
5950-12-9.mol

piperlonguminine Eigenschaften

Schmelzpunkt:
l66-8°C
storage temp. 
Store at -20°C
L?slichkeit
≤3mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
Farbe
White to off-white
InChI
InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+
InChIKey
WHAAPCGHVWVUEX-GGWOSOGESA-N
SMILES
C(NCC(C)C)(=O)/C=C/C=C/C1=CC=C2OCOC2=C1

Sicherheit

piperlonguminine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Piperlonguminine is an alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties. Piperlonguminine (3-12.5 μM) has been shown to dose dependently decrease expression of amyloid precursor protein and amyloid-β peptide in human neuroblastoma cells, suggesting it may have implication in treating Alzheimer’s disease.

Biologische Aktivit?t

Piperlonguminine is an alkaloid amide isolated from the Piper species. It has a wide range of biological properties including anti-inflammatory, anti-tumour, neuroprotective, anti-platelet, anti-melanogenic, anti-fungal and antibacterial activities. In addition, its derivative piperlonguminine acid has Antihyperlipidemic activity.

Einzelnachweise

Chatterjee, Dutta., Tetrahedron Lett., 1797 (1966)
Chatterjee, Dutta., Tetrahedron, 23, 1769 (1967)

piperlonguminine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2,4-Pentadienoyl chloride, 5-(1,3-benzodioxol-5-yl)- 5-(3,4-METHYLENEDIOXYPHENYL)-2,4-PENTADIENOIC ACID Isobutylamin

Downstream Produkte

piperlonguminine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 83)Lieferanten
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5950-12-9()Verwandte Suche:

  • MEXE
  • 5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide
  • 5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2E,4E-pentadienamide
  • mexedrone
  • N-Isobutylpiperamide
  • (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-isobutyl-penta-2,4-dienamide
  • Piperlonguminine
  • Mexedrone MEXE MDPHP BK-2CB
  • Mexedrone Cas no.: 5950-12-9 White crystal 99%
  • Mexedrone Crystal , mexe Pharmaceutical Intermediates CAS 5950-12-9
  • 2,4-Pentadienamide, 5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-, (2E,4E)-
  • TIANFU-CHEM CAS:5950-12-9 5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide
  • Piperlonguminin
  • amide,Inhibitor,inhibit,alkaloid,anti-melanogenic,Bacterial,antibacterial,neuroprotective,antifungal,Piperlonguminine,anti-platelet,Fungal,antitumor,anti-inflammatory,Piper
  • (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-N-isobutylpenta-2,4-dienamide
  • 5950-12-9
  • 5650-12-9
  • for pharmaceutical intermediate
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