Dimethyl cyclopentane-1,3-dicarboxylate
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- CAS-Nr.
- 2435-36-1
- Englisch Name:
- Dimethyl cyclopentane-1,3-dicarboxylate
- Synonyma:
- Cyclopentane-1,3-dicarboxylic acid dimethyl ester;DIMETHYLNORCAMPHORATE;1,3-Bis(methoxycarbonyl)cycl;Norcamphoric acid, dimethyl ester;1,3-Bis(methoxycarbonyl)cyclopentane;Dimethyl=1,3-cyclopentanedicarboxylate;DIMETHYL CYCLOPENTANE-1,3-DICARBOXYLATE;1,3-diMethyl cyclopentane-1,3-dicarboxylate;1-benzyl-4-(4-methylpiperazin-1-yl)piperazine;1,3-Cyclopentanedicarboxylic acid dimethyl ester
- CBNumber:
- CB21411883
- Summenformel:
- C9H14O4
- Molgewicht:
- 186.21
- MOL-Datei:
- 2435-36-1.mol
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Dimethyl cyclopentane-1,3-dicarboxylate Eigenschaften
- Siedepunkt:
- 241℃
- Dichte
- 1.135
- Flammpunkt:
- 113℃
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- Aggregatzustand
- Oil
- Farbe
- Clear Colourless
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Dimethyl cyclopentane-1,3-dicarboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Dimethyl cyclopentane-1,3-dicarboxylate (cas# 2435-36-1) is a useful research chemical, It can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
A 5-L, 3-neck, roundbottom flask was equipped with a mechanical stirrer, a J-KEM temperature controller, and a reflux condenser. The flask was charged with cyclopentane-l,3-dicarboxylic acid(357 g, 2.262 mol) and methanol (1.75 L). The solution was cooled to 7 °C using anice/water bath. Concentrated sulfuric acid (70 mL) was added dropwise over 30 minresulting in an exotherm up to 12 °C. The reaction mixture was heated to reflux andstirred for 16 h when TLC analysis (10 percent methanol/ethyl acetate) indicated that thereaction was complete. The reaction mixture was concentrated, redissolved in methyl- 179 -ATI-2514175vl tert-butyl ether, and washed with saturated aqueous sodium bicarbonate (2 x 150 mL) and brine (2 x 150 mL). The organic layer was dried over sodium sulfate, filtered, and concentrated. The resulting clear oil was dissolved in hexane (2 L) and treated with a 2 N aqueous sodium hydroxide solution (950 mL) until the pH ~ 10. The layers were separated and the aqueous layer was extracted with hexane (4 x 1 L). The organic layers were combined, dried over sodium sulfate, filtered, and concentrated to provide 360 g (100percent) of dimethyl cyclopentane-l,3-dicarboxylate as a clear oil.
Dimethyl cyclopentane-1,3-dicarboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dimethyl cyclopentane-1,3-dicarboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 96)Lieferanten
2435-36-1()Verwandte Suche:
- DIMETHYLNORCAMPHORATE
- 1,3-Cyclopentanedicarboxylic acid dimethyl ester
- Dimethyl=1,3-cyclopentanedicarboxylate
- Norcamphoric acid, dimethyl ester
- 1,3-Bis(methoxycarbonyl)cyclopentane
- 1,3-diMethyl cyclopentane-1,3-dicarboxylate
- 1,3-Cyclopentanedicarboxylic acid, 1,3-diMethyl ester
- 1-benzyl-4-(4-methylpiperazin-1-yl)piperazine
- DIMETHYL CYCLOPENTANE-1,3-DICARBOXYLATE
- 1,3-Bis(methoxycarbonyl)cycl
- Cyclopentane-1,3-dicarboxylic acid dimethyl ester
- 2435-36-1
