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ambuic acid

ambuic acid Struktur
340774-69-8
CAS-Nr.
340774-69-8
Englisch Name:
ambuic acid
Synonyma:
ambuic acid;(2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid;2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
CBNumber:
CB21380277
Summenformel:
C19H26O6
Molgewicht:
350.41
MOL-Datei:
340774-69-8.mol

ambuic acid Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMSO: soluble; Ethanol: soluble; Methanol: soluble
Aggregatzustand
A solid
Farbe
Off-white

Sicherheit

ambuic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi, including F. solani, H. sativum, and C. gramineum, but not P. oryzae, R. solani, or B. cinerea. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 μg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.

ambuic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ambuic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • ambuic acid
  • (2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid
  • 2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
  • 340774-69-8
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