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8-Azaguanosine

8-Azaguanosine Struktur
2133-80-4
CAS-Nr.
2133-80-4
Englisch Name:
8-Azaguanosine
Synonyma:
Azaguanosine;8-Azaguanosine;5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-v-triazolo[4,5-d]pyrimidin-7-one;5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one;7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-;5-Amino-3,4-dihydro-3-(β-D-ribofuranosyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
CBNumber:
CB21245105
Summenformel:
C9H12N6O5
Molgewicht:
284.23
MOL-Datei:
2133-80-4.mol

8-Azaguanosine Eigenschaften

Schmelzpunkt:
250-252 °C (decomp)(Solv: water (7732-18-5))
Dichte
2.49±0.1 g/cm3(Predicted)
pka
8.32±0.20(Predicted)
InChI
InChI=1/C9H12N6O5/c10-9-12-5-2(6(18)13-9)11-1-15(5)8-4(17)3(16)7(14-19)20-8/h1,3-4,7-8,14,16-17,19H,(H3,10,12,13,18)/t3-,4+,7-,8+/s3
InChIKey
DGHTWAQOVOJABA-BKVVLWDVNA-N
SMILES
ON[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)[C@@H]1O |&1:2,4,16,18,r|

Sicherheit

8-Azaguanosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Definition

8-Azaguanosine (azaG) could replace specifically guanosine in the GpUpU codon for valine or the GpCpU codon for alanine in the stimulation of the binding of [14C]aminoacyl-tRNA to ribosomes. However, the binding efficiency in the presence of azaG-containing triplets was lower than in the presence of the natural codons. AzaG could replace guanosine in the 5'-position of codons for valine, alanine, and aspartic acid, as well as in the second position of codons for arginine. However, the template activity of azaG-containing triplets is lower than that of "normal" codons[1].

8-Azaguanosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

8-Azaguanosine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Azaguanosine
  • 5-Amino-3,4-dihydro-3-(β-D-ribofuranosyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
  • 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
  • 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-v-triazolo[4,5-d]pyrimidin-7-one
  • 8-Azaguanosine
  • 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-
  • 2133-80-4
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